Target
Rat IL12B / IL12 p40
Synonyms
IL12B | CLMF p40 | IL-12 p40 | IL-12 subunit p40 | Interleukin-12 beta chain | Interleukin-12 subunit beta | IL12, subunit p40 | Interleukinl-12 | Interleukin 12, p40 | NKSF | CLMF | CLMF2 | IL-12B | NKSF2
Reactivity
Rat
(tested or 100% immunogen sequence identity)
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Immunogen
Rat partial recombinant protein (aa23-321).
Specificity
Rat IL12B / IL12 p40
Applications
- Western blot (0.5 - 1 µg/ml)
Usage
Subunit beta of interleukin 12, also known as interleukin 12B, or IL12B, is a subunit of human interleukin 12. It is mapped to 5q33.3. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease.
Presentation
Lyophilized from PBS, 2.5% BSA, 0.025% sodium azide.
Reconstitution
Reconstitute in sterile distilled water.
Storage
Prior to reconstitution, 4°C. Following reconstitution store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee