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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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IL10RA Antibody (clone 1B1.3A, PE) LS‑C407437
IL10RA antibody LS-C407437 is a PE-conjugated rat monoclonal antibody to mouse IL10RA. Validated for Flow.
Catalog
Size
Price
LS-C407437-50
50 µg
Unavailable
LS-C407437-200
200 µg (0.2 mg/ml)
Unavailable

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Western blot of recombinant IL10RA.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human
Applications: IHC, Western blot

Product Description

IL10RA antibody LS-C407437 is a PE-conjugated rat monoclonal antibody to mouse IL10RA. Validated for Flow.
About IL10RA
IL10RA is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Q13651 NM_001558 NP_001549.2

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Specifications

Target
Mouse IL10RA
Host
Rat
Reactivity
Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal [1B1.3A]
Conjugations
Phycoerythrin
Purification
Purified
Modifications
Unmodified
Applications
  • Flow Cytometry (0.5 µg/10E6 cells)
Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis (The amount of the reagent is suggested to be used <= 0.5 ug /10e6 cells in 100 ul). Since applications vary, the appropriate dilutions must be determined for individual use. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
PBS, pH 7.2, 0.2% BSA, 0.09% sodium azide.
Storage
Store at 4°C. Do not freeze. Protect from light. Store undiluted.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images

Flow Cytometry

IL-10 transgenic mouse splenocytes stained with APC anti-mouse alpha / beta TCR and PE anti-mouse CD210 (IL-10R). This image was taken for the unconjugated form of this product. Other forms have not been tested.
IL-10 transgenic mouse splenocytes stained with APC anti-mouse alpha / beta TCR and PE anti-mouse CD210 (IL-10R). This image was taken for the unconjugated form of this product. Other forms have not been tested.

Flow Cytometry

IL-10 transgenic mouse splenocytes stained with APC anti-mouse alpha / beta TCR and PE anti-mouse CD210 (IL-10R). This image was taken for the unconjugated form of this product. Other forms have not been tested.
IL-10 transgenic mouse splenocytes stained with APC anti-mouse alpha / beta TCR and PE anti-mouse CD210 (IL-10R). This image was taken for the unconjugated form of this product. Other forms have not been tested.

Flow Cytometry

IL-10 transgenic mouse splenocytes stained with APC anti-mouse alpha / beta TCR and PE anti-mouse CD210 (IL-10R). This image was taken for the unconjugated form of this product. Other forms have not been tested.
IL-10 transgenic mouse splenocytes stained with APC anti-mouse alpha / beta TCR and PE anti-mouse CD210 (IL-10R). This image was taken for the unconjugated form of this product. Other forms have not been tested.

Flow Cytometry

IL-10 transgenic mouse splenocytes stained with APC anti-mouse alpha / beta TCR and PE anti-mouse CD210 (IL-10R). This image was taken for the unconjugated form of this product. Other forms have not been tested.
IL-10 transgenic mouse splenocytes stained with APC anti-mouse alpha / beta TCR and PE anti-mouse CD210 (IL-10R). This image was taken for the unconjugated form of this product. Other forms have not been tested.

Requested From: 
Date Requested: 7/19/2018

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