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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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IHCPlus™ SRSF6 / SRP55 Antibody aa143‑192 Polyclonal IHC,WB LS‑B5712

Catalog Number Size Price
LS-B5712-100 100 µl $485 
Anti-SRSF6 / SFRS6 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Jurkat cell lysate. Antibody concentration: 0.5 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-SRSF6 / SFRS6 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Jurkat cell lysate. Antibody concentration: 0.5 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IHCPlus™ SRSF6 / SRP55 Antibody aa143‑192 Polyclonal IHC,WB LS‑B5712

Note: This antibody replaces LS-C80358
Antibody:
Rabbit Polyclonal to Human SRSF6 / SRP55
Application:
IHC, IHC-P, WB
Reactivity:
Human, Monkey, Mouse, Rat, Bat, Bovine, Hamster, Horse, Pig, Rabbit, Zebrafish
Format:
Unconjugated, Unmodified
Other formats:
Price
Catalog Number
$485 
LS-B5712-100
Toll Free North America
866-819-4732

Overview

Antibody:
Rabbit Polyclonal to Human SRSF6 / SRP55
Application:
IHC, IHC-P, WB
Reactivity:
Human, Monkey, Mouse, Rat, Bat, Bovine, Hamster, Horse, Pig, Rabbit, Zebrafish
Format:
Unconjugated, Unmodified
Other formats:

Specifications

Description
SRP55 antibody LS-B5712 is an unconjugated rabbit polyclonal antibody to SRP55 (SRSF6 ) from human, mouse, rat and other species. Validated for IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 2 publications.
Target
Human SRSF6 / SRP55
Host
Rabbit
Reactivity
Human, Monkey, Mouse, Rat, Bat, Bovine, Hamster, Horse, Pig, Rabbit, Zebrafish (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated. Also available conjugated with Biotin, FITC, HRP.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (5 µg/ml)
  • Western blot
  • (applications tested for the base form of this product only)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Synthetic peptide located between aa143-192 of human SRSF6 (Q13247, NP_006266). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Galago, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Bovine, Bat, Rabbit, Horse, Pig, Opossum (100%); Turkey, Zebra finch, Chicken, Platypus (85%); Stickleback, Zebrafish (84%).
Blocking Peptide
LS-E14865 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-B5712. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
aa143-192
Specificity
Human SRSF6 / SFRS6
Usage
ELISA titer using peptide based assay: 1:62500. Western Blot: Suggested dilution at 0.5 ug/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1:50000 - 100000 as second antibody.
Presentation
PBS, 0.09% sodium azide, 2% sucrose
Storage
Short term: Store at 2-8°C. Long term: Aliquot and store at -20°C. Avoid freeze/thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About SRSF6 / SRP55
Q13247 NM_006275 NP_006266.2

Validation

Anti-SRSF6 / SFRS6 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
IHC Validated
Anti-SRSF6 / SFRS6 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-SRSF6 / SFRS6 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Publications (2)

Aberrant splicing of HTT generates the pathogenic exon 1 protein in Huntington disease. Sathasivam K, Neueder A, Gipson TA, Landles C, Benjamin AC, Bondulich MK, Smith DL, Faull RL, Roos RA, Howland D, Detloff PJ, Housman DE, Bates GP. Proceedings of the National Academy of Sciences of the United States of America. 2013 110:2366-70. (IP; Mouse)

Huntington's disease is a four-repeat tauopathy with tau nuclear rods. Fern[Character e1]ndez-Nogales M, Cabrera JR, Santos-Galindo M, Hoozemans JJ, Ferrer I, Rozemuller AJ, Hern[Character e1]ndez F, Avila J, Lucas JJ. Nature medicine. Aug;20:881-5.

Reviews (0)

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Requested From: United States
Date Requested: 8/20/2019
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