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| Catalog Number | Size | Price |
|---|---|---|
| LS-A975-50 | 50 µg (1 mg/ml) | $440 |
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PathPlus™ Polyclonal Rabbit anti‑Human PTGER3 / EP3 Antibody (Cytoplasmic Domain, IHC) LS‑A975
PathPlus™ Polyclonal Rabbit anti‑Human PTGER3 / EP3 Antibody (Cytoplasmic Domain, IHC) LS‑A975
Antibody:
PTGER3 / EP3 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Monkey, Bat
Format:
Unconjugated, Unmodified
Overview
Antibody:
PTGER3 / EP3 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Monkey, Bat
Format:
Unconjugated, Unmodified
Specifications
Description
Receptor for prostaglandin E2 (PGE2); the EP3 receptor may be involved in inhibition of gastric acid secretion, modulation of neurotransmitter release in central and peripheral neurons, inhibition of sodium and water reabsorption in kidney tubulus and contraction in uterine smooth muscle. The activity of this receptor can couple to both the inhibition of adenylate cyclase mediated by G-I proteins, and to an elevation of intracellular calcium. The various isoforms have identical ligand binding properties but can interact with different second messenger systems.
References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human PTGER3 / EP3
Synonyms
PTGER3 | Ep3 prostanoid receptor | Ep3 receptor | EP3-I | EP3e | EP3-II | EP3-III | EP3-IV | PGE receptor, EP3 subtype | Prostaglandin receptor (PGE-2) | Prostaglandin ep3 receptor | Prostanoid EP3 receptor | PGE receptor EP3 subtype | Pge2 receptor ep3 | PGE2 receptor EP3 subtype | Prostaglandin E receptor 3 | Prostaglandin e2 receptor ep3 | EP3 | Ep3 subtype pge2 receptor | PGE2-R | Prostaglandin E receptor EP3
Host
Rabbit
Reactivity
Human, Monkey, Bat
(tested or 100% immunogen sequence identity)
Predicted
Mouse (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 17 amino acid peptide from 1st cytoplasmic domain of human PTGER3 / EP3. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Panda, Bat (100%); Mouse (94%); Xenopus (88%); Bovine, Pig, Opossum (82%).
Epitope
Cytoplasmic Domain
Specificity
Human PTGER3 / EP3. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Applications
- IHC
- IHC - Paraffin (1 - 3 µg/ml)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About PTGER3 / EP3
Validation
Breast carcinoma
Breast carcinoma
Human, Breast: Formalin-Fixed Paraffin-Embedded (FFPE)
Human, Breast: Formalin-Fixed Paraffin-Embedded (FFPE)
Colon, Carcinoma
Colon, Carcinoma
Pancreas, carcinoma
Pancreas, carcinoma
Ovary, carcinoma
Ovary, carcinoma
Anti-PTGER3 / EP3 antibody IHC of human brain, hippocampus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-PTGER3 / EP3 antibody IHC of human brain, hippocampus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-PTGER3 / EP3 antibody IHC of human brain, hippocampus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-PTGER3 / EP3 antibody IHC of human brain, hippocampus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Pancreas, Carcinoma
Pancreas, Carcinoma
Breast, Carcinoma
Breast, Carcinoma
Anti-PTGER3 / EP3 antibody IHC of human brain, glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-PTGER3 / EP3 antibody IHC of human brain, glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
See More About...
LSBio Ratings
PathPlus™ PTGER3 / EP3 Antibody (Cytoplasmic Domain) for IHC LS-A975 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human, Monkey
Applications:
IHC, IHC - Paraffin
Species:
Human, Monkey, Mouse, Rat, Bat, Horse, Rabbit
Applications:
IHC, IHC - Paraffin, ELISA
Species:
Human, Monkey, Bovine, Horse, Pig
Applications:
IHC, IHC - Paraffin
Species:
Human
Applications:
IHC, IHC - Paraffin, ICC, Western blot
Species:
Human
Applications:
IHC, IHC - Paraffin, Immunofluorescence, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Species:
Human, Monkey
Applications:
IHC, IHC - Paraffin
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/18/2024
Date Requested: 4/18/2024
