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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

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Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Catalog Number Size Price
LS-A730-50 50 µg (0.23 mg/ml) $425 
PDE6A / PDE6 Alpha Antibody - Anti-PDE6A / PDE6 Alpha antibody IHC of human eye, retina. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHCPlus™ Polyclonal Rabbit anti‑Human PDE6A / PDE6 Alpha Antibody (N‑Terminus, IHC) LS‑A730

IHCPlus™ Polyclonal Rabbit anti‑Human PDE6A / PDE6 Alpha Antibody (N‑Terminus, IHC) LS‑A730

Note: This antibody replaces LS-C90180, LS-C42461
Antibody:
Rabbit Polyclonal to Human PDE6A / PDE6 Alpha
Application:
IHC, IHC-P
Reactivity:
Human, Monkey, Mouse, Rat, Hamster
Format:
Unconjugated, Unmodified
Other formats:
Price
Catalog Number
$425 
LS-A730-50
50 µg
0.23 mg/ml

Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
Rabbit Polyclonal to Human PDE6A / PDE6 Alpha
Application:
IHC, IHC-P
Reactivity:
Human, Monkey, Mouse, Rat, Hamster
Format:
Unconjugated, Unmodified
Other formats:

Specifications

Description
PDE6 Alpha antibody LS-A730 is an unconjugated rabbit polyclonal antibody to PDE6 Alpha (PDE6A) (N-Terminus) from human. It is reactive with human, mouse, rat and other species. Validated for IHC. Tested on 20 paraffin-embedded human tissues.
Target
Human PDE6A / PDE6 Alpha
Synonyms
PDE6A | Alpha-PDE | CGMP phosphodiesterase alpha | CGPR-A | PDE6alpha | PDE V-B1 | PDEA | Phosphodiesterase 6a | RP43 | GMP-PDE alpha
Host
Rabbit
Reactivity
Human, Monkey, Mouse, Rat, Hamster (tested or 100% immunogen sequence identity)
Predicted
Dog, Rabbit (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (10 - 15 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Synthetic 18 amino acid peptide from N-Terminus of human PDE6A / PDE6 Alpha. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster (100%); Dog, Panda, Rabbit (94%); Bovine, Bat, Elephant (89%); Horse, Opossum (83%).
Blocking Peptide
LS-E29248 - Liquid - 50 µg - $145.00
Immunizing peptide used to generate LS-A730. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
N-Terminus
Specificity
Human PDE6A / PDE6 Alpha. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Usage
Immunohistochemistry: The unconjugated form was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for the unconjugated form was determined to be 10 ug/ml.
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About PDE6A / PDE6 Alpha
P16499 NM_000440 NP_000431.2

Validation

PDE6A / PDE6 Alpha Antibody - Anti-PDE6A / PDE6 Alpha antibody IHC of human eye, retina. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-PDE6A / PDE6 Alpha antibody IHC of human eye, retina. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-PDE6A / PDE6 Alpha antibody IHC of human eye, retina. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

LSBio Ratings

IHC-plus™ PDE6A / PDE6 Alpha Antibody (N-Terminus) for IHC LS-A730 has an LSBio Rating of
Laboratory Validation Score (4)

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Requested From: United States
Date Requested: 6/5/2020