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| Catalog Number | Size | Price |
|---|---|---|
| LS-A7962-50 | 50 µg (1 mg/ml) | $460 |
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PathPlus™ Polyclonal Rabbit anti‑Human PAK6 Antibody (Linker Domain, IHC) LS‑A7962
PathPlus™ Polyclonal Rabbit anti‑Human PAK6 Antibody (Linker Domain, IHC) LS‑A7962
Antibody:
PAK6 Rabbit anti-Human Polyclonal (Linker Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Overview
Antibody:
PAK6 Rabbit anti-Human Polyclonal (Linker Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Specifications
Description
PAK6 is a member of a family of p21-stimulated serine/threonine protein kinases, which contain an amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. These kinases function in a number of cellular processes, including cytoskeleton rearrangement, apoptosis, and the mitogen-activated protein (MAP) kinase signaling pathway. The protein encoded by this gene interacts with androgen receptor (AR) and translocates to the nucleus, where it is involved in transcriptional regulation. Changes in expression of this gene have been linked to prostate cancer. Alternative splicing results in multiple transcript variants.
References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human PAK6
Synonyms
PAK6 | PAK5 | p21-activated kinase 6 | p21-activated protein kinase 6 | PAK-5 | PAK-6 | p21(CDKN1A)-activated kinase 6
Host
Rabbit
Reactivity
Human
(tested or 100% immunogen sequence identity)
Predicted
Monkey, Bovine (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 19 amino acid peptide from Linker domain of human PAK6. Percent identity with other species by BLAST analysis: Human, Gorilla, Orangutan, Gibbon (100%); Monkey, Panda, Bovine (95%); Marmoset, Rat, Elephant, Bat, Dog, Rabbit, Horse (89%); Mouse (84%).
Epitope
Linker Domain
Specificity
Human PAK6. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except AGBL5 (42%).
Applications
- IHC
- IHC - Paraffin (4.8 µg/ml)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About PAK6
Validation
Colon, Carcinoma
Colon, Carcinoma
Lung, Non Small-Cell Carcinoma
Lung, Non Small-Cell Carcinoma
Breast, carcinoma
Breast, carcinoma
Anti-PAK6 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-PAK6 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Brain, Glioblastoma
Brain, Glioblastoma
See More About...
LSBio Ratings
PathPlus™ PAK6 Antibody (Linker Domain) for IHC LS-A7962 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human, Monkey, Dog, Horse
Applications:
IHC, IHC - Paraffin
Species:
Human, Monkey, Dog, Horse
Applications:
IHC, IHC - Paraffin
Source:
E. coli
Tag:
6His, N-terminus
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/24/2024
Date Requested: 4/24/2024
