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| Catalog Number | Size | Price |
|---|---|---|
| LS-A6644-50 | 50 µg (1 mg/ml) | $440 |
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PathPlus™ Polyclonal Rabbit anti‑Human MRGPRX2 / MRGX2 Antibody (Extracellular Domain, IHC) LS‑A6644
PathPlus™ Polyclonal Rabbit anti‑Human MRGPRX2 / MRGX2 Antibody (Extracellular Domain, IHC) LS‑A6644
Antibody:
MRGPRX2 / MRGX2 Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Monkey
Format:
Unconjugated, Unmodified
Overview
Antibody:
MRGPRX2 / MRGX2 Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Monkey
Format:
Unconjugated, Unmodified
Specifications
Description
MRGX2 is a G-protein coupled receptor that may regulate nociceptor function and development, including the sensation or modulation of pain. Cortistatin-14 seems to be a high potency ligand at this receptor. Cortistatin has several biological functions including roles in sleep regulation locomotor activity, and cortical function. It has been reported to be expressed in regions of the brain, pituitary, thyroid, pancreas, testis, and ovary, as well as in neuroendocrine tumors.
References: J Pathol 2005; 207: 336–345
Target
Human MRGPRX2 / MRGX2
Synonyms
MRGPRX2 | MRGX2 | MAS-related GPR, member X2
Host
Rabbit
Reactivity
Human, Monkey
(tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 14 amino acid peptide from 2nd extracellular domain of human MRGPRX2 / MRGX2. Percent identity with other species by BLAST analysis: Human, Orangutan, Monkey (100%); Chimpanzee, Gorilla, Gibbon, Marmoset (86%).
Epitope
Extracellular Domain
Specificity
Human MRGPRX2 / MRGX2. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except MRGPRX1 (71%), MRGPRX4 (64%), MRGPRX3 (57%).
Applications
- IHC
- IHC - Paraffin (10 - 20 µg/ml)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About MRGPRX2 / MRGX2
Validation
Anti-MRGPRX2 / MRGX2 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-MRGPRX2 / MRGX2 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Brain, Hypothalamus, neurons of the dorsomedial nucleus
Brain, Hypothalamus, neurons of the dorsomedial nucleus
Brain, amygdala, neurons and glia
Brain, amygdala, neurons and glia
Anti-MRGPRX2 / MRGX2 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-MRGPRX2 / MRGX2 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-MRGPRX2 / MRGX2 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-MRGPRX2 / MRGX2 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-MRGPRX2 / MRGX2 antibody IHC of human spinal cord, dorsal root ganglion. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-MRGPRX2 / MRGX2 antibody IHC of human spinal cord, dorsal root ganglion. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Human Lung: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Lung: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Breast: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Breast: Formalin-Fixed, Paraffin-Embedded (FFPE)
See More About...
LSBio Ratings
PathPlus™ MRGPRX2 / MRGX2 Antibody (Extracellular Domain) for IHC LS-A6644 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Human
Applications:
Western blot, ELISA
Species:
Human
Applications:
IHC, IHC - Paraffin, IHC - Frozen
Source:
E. coli
Tag:
6His, N-terminus
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/23/2024
Date Requested: 4/23/2024
