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| Catalog Number | Size | Price |
|---|---|---|
| LS-B6625-50 | 50 µl (0.5 mg/ml) | $460 |
1 of 2
2 of 2
Polyclonal Rabbit anti‑Human KL / Klotho Antibody (aa251‑300, IHC, WB) LS‑B6625
Polyclonal Rabbit anti‑Human KL / Klotho Antibody (aa251‑300, IHC, WB) LS‑B6625
Note: This antibody replaces LS-C107623
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Specifications
Description
Klotho antibody LS-B6625 is an unconjugated rabbit polyclonal antibody to human Klotho (KL) (aa251-300). Validated for IHC and WB. Cited in 3 publications.
Host
Rabbit
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG
Polyclonal
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic peptide located between aa251-300 of human KL (Q9UEF7-2). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Monkey, Galago, Marmoset, Mouse, Rat, Elephant, Dog, Bat, Rabbit, Horse, Guinea pig, Platypus (100%); Gibbon, Bovine, Pig, Opossum (92%).
Epitope
aa251-300
Specificity
Human KL / Klotho
Applications
- IHC
- IHC - Paraffin (5 µg/ml)
- Western blot (0.2 - 1 µg/ml)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
Western Blot: Suggested dilution at 1µg/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as second antibody. ELISA titer in peptide based assay: 1:62500.
Presentation
PBS, 0.09% sodium azide, 2% sucrose
Storage
Short term: Store at 2-8°C. Long term: Aliquot and store at -20°C. Avoid freeze/thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About KL / Klotho
LSBio Ratings
KL / Klotho Antibody (aa251-300) for IHC, WB/Western LS-B6625 has an LSBio Rating of
Publications (4.2)
Learn more about The LSBio Ratings Algorithm
Publications (3)
Soluble klotho as a marker of renal fibrosis and podocyte injuries in human kidneys. Cho NJ, Han DJ, Lee JH, Jang SH, Kang JS, Gil HW, Park S, Lee EY. PloS one. 2018 March;13:e0194617. (Human)
Protective effects of klotho on palmitate-induced podocyte injury in diabetic nephropathy. Jeong Suk Kang , Seung Seob Son, Ji-Hye Lee, Seong Woo Lee , Ah Reum Jeong, Eun Soo Lee, Seung-Kuy Cha, Choon Hee Chung, Eun Young Lee. PloS one. 2021 Apr;16:e0250666.
Down-expression of klotho in canine mammary gland tumors and its prognostic significance. Heaji Chung, Sungin Lee, Geon A Kim, Wan Hee Kim. PloS one. 2022 June;17:e0265248.
Customer Reviews (0)
Featured Products
Species:
Human, Mouse, Rat
Applications:
IHC, IHC - Paraffin, Immunofluorescence, Western blot, ELISA
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/23/2024
Date Requested: 4/23/2024
