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IHCPlus™ HTT / Huntingtin Antibody aa2703‑2911 Monoclonal IHC,IP,WB LS‑B6236

Catalog Number Size Price
LS-B6236-50 50 µg (1 mg/ml) $485 
Anti-HTT / Huntingtin antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

IHCPlus™ HTT / Huntingtin Antibody aa2703‑2911 Monoclonal IHC,IP,WB LS‑B6236

Note: This antibody replaces LS-C24586
Antibody:
Mouse Monoclonal to Human HTT / Huntingtin
Application:
IHC, IHC-P, IHC-Fr, WB, IP
Reactivity:
Human, Rabbit
Format:
Unconjugated, Unmodified
Other formats:
Price
Catalog Number
$485 
LS-B6236-50
Toll Free North America
866-819-4732

Overview

Antibody:
Mouse Monoclonal to Human HTT / Huntingtin
Application:
IHC, IHC-P, IHC-Fr, WB, IP
Reactivity:
Human, Rabbit
Format:
Unconjugated, Unmodified
Other formats:

Specifications

Description
Huntingtin antibody LS-B6236 is an unconjugated mouse monoclonal antibody to Huntingtin (HTT ) from human and rabbit. Validated for IHC, IP and WB. Tested on 20 paraffin-embedded human tissues.
Target
Human HTT / Huntingtin
Host
Mouse
Reactivity
Human, Rabbit (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal
Conjugations
Unconjugated. Also available conjugated with AP, Biotin, FITC, HRP, PE.
Purification
Protein G purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (10 µg/ml)
  • IHC - Frozen
  • Western blot
  • Immunoprecipitation
  • (applications tested for the base form of this product only)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Recombinant protein corresponding to amino acids 2703 - 2911 of huntingtin.
Epitope
aa2703-2911
Specificity
Reacts with an epitope corresponding to the human HDC region (2703-2911 amino acids) of the huntingtin protein. Detects a 350kD band on Western Blots but also detects smaller degradation products of Huntingtin. Recognizes both denatured and native Huntingtin in human brain. The combined use of this antibody, LS-C24585 and LS-demonstrates that huntingtin is enriched in neuronal cells in the brain.
Usage
Suitable for use in Immunohistochemistry, Immunoprecipitation and Western Blot. Immunohistochemistry: Frozen, FFPE (human). Increased cytoplasmic staining, relative to nuclear, has been reported using formaldehyde as a fixative compared with acetone/methanol. Positive control: IHC frozen-rabbit btain.
Presentation
PBS, 0.09% Sodium Azide
Storage
Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About HTT / Huntingtin
P42858 NM_002111 NP_002102.4

Validation

Anti-HTT / Huntingtin antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
IHC Validated
Anti-HTT / Huntingtin antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-HTT / Huntingtin antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

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Requested From: United States
Date Requested: 8/17/2019
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