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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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IHCPlus™ HTR7 / 5HT7 Receptor Antibody C‑Terminus Polyclonal ELISA,IHC LS‑A7991

Catalog Number Size Price
LS-A7991-50 50 µg (1 mg/ml) $425 
Anti-5HT7 Receptor antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHCPlus™ HTR7 / 5HT7 Receptor Antibody C‑Terminus Polyclonal ELISA,IHC LS‑A7991

Note: This antibody replaces LS-C42659
Antibody:
Rabbit Polyclonal to Human HTR7 / 5HT7 Receptor
Application:
IHC, IHC-P, ELISA
Reactivity:
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Hamster, Horse, Pig
Format:
Unconjugated, Unmodified
Other formats:
Price
Catalog Number
$425 
LS-A7991-50
Toll Free North America
866-819-4732

Overview

Antibody:
Rabbit Polyclonal to Human HTR7 / 5HT7 Receptor
Application:
IHC, IHC-P, ELISA
Reactivity:
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Hamster, Horse, Pig
Format:
Unconjugated, Unmodified
Other formats:

Specifications

Description
5HT7 Receptor antibody LS-A7991 is an unconjugated rabbit polyclonal antibody to 5HT7 Receptor (HTR7 ) from human, mouse, rat and other species. Validated for ELISA and IHC. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.
Target
Human HTR7 / 5HT7 Receptor
Host
Rabbit
Reactivity
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Hamster, Horse, Pig (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (10 - 20 µg/ml)
  • ELISA
  • (applications tested for the base form of this product only)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Synthetic 20 amino acid peptide from C-terminus of human 5HT7 Receptor. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Bovine, Bat, Dog, Hamster, Panda, Horse, Pig, Guinea pig (100%); Opossum (90%); Elephant (85%); Pufferfish, Zebrafish (80%).
Blocking Peptide
LS-E29304 - Liquid - 50 µg 1 mg/ml - $145.00
Immunizing peptide used to generate LS-A7991. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
C-Terminus
Specificity
Human 5HT7 Receptor. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Usage
Immunohistochemistry: LS-A7991 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-A7991 was determined to be 10 ug/ml.
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About HTR7 / 5HT7 Receptor
P34969 NM_019859 NP_062873.1

Validation

Anti-5HT7 Receptor antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
IHC Validated
Anti-5HT7 Receptor antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-5HT7 Receptor antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Publications (1)

5-HT is a potent relaxant in rat superior mesenteric veins. Watts SW, Darios ES, Seitz BM, Thompson JM. Pharmacology research & perspectives. 2015 3:e00103. (IHC; Rat)

Reviews (0)

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Anti-5HT7 Receptor antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Requested From: United States
Date Requested: 8/18/2019
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