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| Catalog Number | Size | Price |
|---|---|---|
| LS-A111-50 | 50 µg (1 mg/ml) | $460 |
1 of 2
2 of 2
PathPlus™ Polyclonal Rabbit anti‑Human GPR22 Antibody (Cytoplasmic Domain, IHC) LS‑A111
PathPlus™ Polyclonal Rabbit anti‑Human GPR22 Antibody (Cytoplasmic Domain, IHC) LS‑A111
Antibody:
GPR22 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Monkey, Bat, Hamster, Horse, Chicken, Xenopus, Zebrafish
Format:
Unconjugated, Unmodified
Overview
Antibody:
GPR22 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Monkey, Bat, Hamster, Horse, Chicken, Xenopus, Zebrafish
Format:
Unconjugated, Unmodified
Specifications
Description
GPR22 is an orphan G protein-coupled receptor (GPCR). It is involved in ciliogenesis in zebrafish, and shows a highly restricted expression pattern in humans and rodents, with abundant and selective expression in the brain and heart. GPR22 protein expression has been detected in cardiac myocytes and coronary arteries by immunohistochemistry. It has been hypothesized to have a protective role for in response to hemodynamic stress resulting from increased afterload in the heart.
References: PLOS One/doi.org/10.1371/journal.pone.0110484; 01 AUG 2008https://doi.org/10.1152/ajpheart.00368.2008
Host
Rabbit
Reactivity
Human, Monkey, Bat, Hamster, Horse, Chicken, Xenopus, Zebrafish
(tested or 100% immunogen sequence identity)
Predicted
Mouse, Rat, Bovine, Pig, Rabbit (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 20 amino acid peptide from 3rd cytoplasmic domain of human GPR22. Percent identity with other species by BLAST analysis: Human, Gorilla, Monkey, Marmoset, Bat, Hamster, Elephant, Panda, Horse, Turkey, Chicken, Platypus, Lizard, Xenopus, Pufferfish, Zebrafish, Stickleback (100%); Mouse, Rat, Rabbit, Pig (95%); Bovine (90%).
Epitope
Cytoplasmic Domain
Specificity
Human GPR22. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Applications
- IHC
- IHC - Paraffin (4 µg/ml)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About GPR22
Validation
Anti-GPR22 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GPR22 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Brain, Hypothalamus
Brain, Hypothalamus
See More About...
LSBio Ratings
PathPlus™ GPR22 Antibody (Cytoplasmic Domain) for IHC LS-A111 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human, Monkey, Bovine, Horse, Pig, Rabbit
Applications:
IHC, IHC - Paraffin
Species:
Human, Monkey, Mouse, Rat, Bat, Bovine, Hamster, Horse, Pig, Rabbit, Chicken, Xenopus, Zebrafish
Applications:
IHC, IHC - Paraffin
Species:
Human, Mouse
Applications:
Immunofluorescence, Peptide Enzyme-Linked Immunosorbent Assay
Species:
Human, Mouse
Applications:
Immunofluorescence, ELISA
Reactivity:
Mouse
Range:
2.47-200 ng/ml
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/16/2024
Date Requested: 4/16/2024
