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Catalog Number Size Price
LS-B4846-50 50 µl (1.19 mg/ml) $440 
DNASE1 / DNase I Antibody - Anti-DNase I antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
DNASE1 / DNase I Antibody - Anti-DNase I antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
DNASE1 / DNase I Antibody - Western blot using MOLT-4 cell extracts. Antibody diluted 1:1000
DNASE1 / DNase I Antibody - Anti-DNase I antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
DNASE1 / DNase I Antibody - Anti-DNase I antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
DNASE1 / DNase I Antibody - Western blot using MOLT-4 cell extracts. Antibody diluted 1:1000
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IHC‑plus™ Polyclonal Rabbit anti‑Human DNASE1 / DNase I Antibody (IHC, WB) LS‑B4846

IHC‑plus™ Polyclonal Rabbit anti‑Human DNASE1 / DNase I Antibody (IHC, WB) LS‑B4846

Note: This antibody replaces LS-C109425
Antibody:
DNASE1 / DNase I Rabbit anti-Human Polyclonal Antibody
Application:
IHC, IHC-P, ICC, WB
Reactivity:
Human
Format:
Unconjugated, Unmodified
Price
Catalog Number
$440
LS-B4846-50
Toll Free North America
206-374-1102
For Research Use Only

Overview

Antibody:
DNASE1 / DNase I Rabbit anti-Human Polyclonal Antibody
Application:
IHC, IHC-P, ICC, WB
Reactivity:
Human
Format:
Unconjugated, Unmodified

Specifications

Description
DNase I antibody LS-B4846 is an unconjugated rabbit polyclonal antibody to human DNase I (DNASE1). Validated for ICC, IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 3 publications.
Target
Human DNASE1 / DNase I
Synonyms
DNASE1 | Deoxyribonuclease I | Deoxyribonuclease i precursor | DNase I | DNL1 | DRNI | Deoxyribonuclease-1 | DNase I, lysosomal
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Recombinant protein corresponding to human DNase I.
Specificity
Human DNase I. Predicted cross-reactivity based on amino acid sequence homology: rabbit (81%), dogs (81%).
Applications
  • IHC
  • IHC - Paraffin (10 µg/ml)
  • ICC (1:100 - 1:1000)
  • Western blot (1:500 - 1:3000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Presentation
1X PBS, pH 7, 0.025% ProClin™ 300, 20% Glycerol
Storage
Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles. Store undiluted.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About DNASE1 / DNase I
P24855 NM_005223 NP_005214.2

Validation

DNASE1 / DNase I Antibody - Anti-DNase I antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-DNase I antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-DNase I antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

DNASE1 / DNase I Antibody - Anti-DNase I antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-DNase I antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-DNase I antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

LSBio Ratings

IHC-plus™ DNASE1 / DNase I Antibody for IHC, ICC, WB/Western LS-B4846 has an LSBio Rating of
Publications (4.2)
Laboratory Validation Score (4)

Publications (3)

TNFα Amplifies DNaseI Expression in Renal Tubular Cells while IL-1β Promotes Nuclear DNaseI Translocation in an Endonuclease-Inactive Form. Thiyagarajan D, Rekvig OP, Seredkina N. PloS one. 2015 10:e0129485. (IHC, WB; Mouse, Human)

IL-1ß Promotes a New Function of DNase I as a Transcription Factor for the Fas Receptor Gene. Thiyagarajan D, Pedersen HL, Seredkina N, Horvei KD, Arranz L, Sonneveld R, Nijenhuis T, van der Vlag J, Rekvig OP. Frontiers in cell and developmental biology. 2018 February;6:7. (Human)

Lupus nephritis: low urinary DNase I levels reflect loss of renal DNase I and may be utilized as a biomarker of disease progression. Pedersen HL, Horvei KD, Thiyagarajan D, Norby GE, Seredkina N, Moroni G, Eilertsen GØ, Holdaas H, Strøm EH, Bakland G, Meroni PL, Rekvig OP. The journal of pathology Clinical research. 2018 July;4:193-203.

Customer Reviews (0)


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Requested From: United States
Date Requested: 7/4/2022