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| Catalog Number | Size | Price |
|---|---|---|
| LS-B5729-50 | 50 µl (0.5 mg/ml) | $460 |
1 of 2
2 of 2
Polyclonal Rabbit anti‑Human ABCB4 / MDR3 Antibody (aa252‑301, IHC, WB) LS‑B5729
Polyclonal Rabbit anti‑Human ABCB4 / MDR3 Antibody (aa252‑301, IHC, WB) LS‑B5729
Note: This antibody replaces LS-C110652
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Specifications
Description
MDR3 antibody LS-B5729 is an unconjugated rabbit polyclonal antibody to human MDR3 (ABCB4) (aa252-301). Validated for IHC and WB. Cited in 2 publications.
Target
Human ABCB4 / MDR3
Synonyms
ABCB4 | ABC21 | ICP3 | GBD1 | MDR3 | MDR2 | Multidrug resistance protein 3 | Multiple drug resistance 3 | P-glycoprotein 3 | Pgy2 | PGY3 | PFIC-3 | MDR2/3
Host
Rabbit
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic peptide located between aa252-301 of human ABCB4 (A4D1D4, NP_000434). Percent identity by BLAST analysis: Human, Chimpanzee, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Rabbit (100%); Galago, Panda, Opossum (92%); Bovine (85%).
Epitope
aa252-301
Specificity
Human ABCB4
Applications
- IHC
- IHC - Paraffin (5 µg/ml)
- Western blot (0.2 - 1 µg/ml)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
Western Blot: Suggested dilution at 1 ug/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.
Presentation
PBS, 0.09% sodium azide, 2% sucrose
Storage
Short term: Store at 2-8°C. Long term: Aliquot and store at -20°C. Avoid freeze/thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About ABCB4 / MDR3
LSBio Ratings
ABCB4 / MDR3 Antibody (aa252-301) for IHC, WB/Western LS-B5729 has an LSBio Rating of
Publications (4.1)
Learn more about The LSBio Ratings Algorithm
Publications (2)
ABCB4 is frequently epigenetically silenced in human cancers and inhibits tumor growth. Kiehl S, Herkt SC, Richter AM, Fuhrmann L, El-Nikhely N, Seeger W, Savai R, Dammann RH. Scientific reports. 4:6899.
Gene therapy for progressive familial intrahepatic cholestasis type 3 in a clinically relevant mouse model. Weber ND, Odriozola L, Martínez-García J, Ferrer V, Douar A, Bénichou B, González-Aseguinolaza G, Smerdou C. Nature communications. 2019 December;10:5694.
Customer Reviews (0)
Featured Products
Species:
Human
Applications:
IHC, IHC - Frozen, Western blot
Species:
Human, Mouse, Rat
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Human
Applications:
IHC, IHC - Frozen, ICC, Western blot, Flow Cytometry
Species:
Human
Applications:
IHC - Paraffin, Immunofluorescence, ELISA
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/24/2024
Date Requested: 4/24/2024
