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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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IGF2R / CD222 Antibody (aa1148‑1365, Biotin) LS‑C297721
CD222 antibody LS-C297721 is a biotin-conjugated rabbit polyclonal antibody to mouse CD222 (IGF2R). Validated for WB.
Catalog
Size
Price
LS-C297721-100
100 µl (0.5 mg/ml)
Unavailable

Popular IGF2R / CD222 Products

Antibody
Species: Human, Primate
Applications: Flow Cytometry
Permeabilized Peripheral Human Granulocytes stained with Mouse anti Human CD222: APC. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Rhesus monkey
Applications: Flow Cytometry
Anti-IGF2R antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2351 concentration 10 ug/ml.
Species: Bovine, Human, Monkey
Applications: IHC, IHC - Paraffin, ICC, Western blot, Immunoprecipitation
Anti-IGF2R antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5653 dilution 1:100.
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Immunofluorescence, Peptide Enzyme-Linked Immunosorbent Assay
Immunohistochemical analysis of CD222 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Species: Human, Mouse, Bovine
Applications: IHC, IHC - Paraffin, ICC, Immunofluorescence, Western blot

Product Description

CD222 antibody LS-C297721 is a biotin-conjugated rabbit polyclonal antibody to mouse CD222 (IGF2R). Validated for WB.
About IGF2R / CD222
Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2. Acts as a positive regulator of T-cell coactivation, by binding DPP4. P11717 NM_000876 NP_000867.2

IGF2R Antibody, CD222 antigen Antibody, CIMPR Antibody, CI Man-6-P receptor Antibody, CI-MPR Antibody, IGF-II receptor Antibody, MPR 300 Antibody, MPR1 Antibody, MPRI Antibody, M6P-R Antibody, M6P/IGF2R Antibody, CD222 Antibody, M6P/IGF2 receptor Antibody


Specifications

Target
Mouse IGF2R / CD222
Host
Rabbit
Reactivity
Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Biotin. Also available Unconjugated or conjugated with FITC.
Purification
Affinity purified
Modifications
Unmodified
Applications
  • Western blot
  • (applications tested for the base form of this product only)
Immunogen
IGF2R / CD222 antibody was raised against recombinant IGF2R (Val1148-Gln1365) expressed in E. coli.
Epitope
aa1148-1365
Specificity
Mouse IGF2R / CD222
Usage
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Storage
Store frozen product at or below -20°C. Thawed product may be stored for 2-4 weeks at 4°C. For optimal storage, aliquot to smaller portions and store at -20°C to -70°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

Western blot of recombinant IGF2R / CD222.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of recombinant IGF2R / CD222. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Western blot of recombinant IGF2R / CD222.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of recombinant IGF2R / CD222. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Western blot of recombinant IGF2R / CD222.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of recombinant IGF2R / CD222. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Western blot of recombinant IGF2R / CD222.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of recombinant IGF2R / CD222. This image was taken for the unconjugated form of this product. Other forms have not been tested.


Requested From: 
Date Requested: 6/18/2018

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