IgE

Immunoglobulin E (IgE) is a kind of antibody (or immunoglobulin (Ig) "isotype") that has only been found in mammals. Monomers of IgE consist of two heavy chains (epsilon chain) and two light chains, with the epsilon chain containing 4 Ig-like constant domains. IgE's main function is immunity to parasites such as helminths like Schistosoma mansoni, Trichinella spiralis, and Fasciola hepatica. IgE is utilized during immune defense against certain protozoan parasites such as Plasmodium falciparum. IgE also has an essential role in type I hypersensitivity, which manifests various allergic diseases, such as allergic asthma, most types of sinusitis, allergic rhinitis, food allergies, and specific types of chronic urticaria and atopic dermatitis. IgE also plays a pivotal role in responses to allergens, such as: anaphylactic drugs, bee stings, and antigen preparations used in desensitization immunotherapy. Although IgE is typically the least abundant isotype—blood serum IgE levels in a normal ("non-atopic") individual are only 0.05% of the Ig concentration, compared to 75% for the IgGs at 10 mg/ml, which are the isotypes responsible for most of the classical adaptive immune response—it is capable of triggering the most powerful inflammatory reactions.

IgE Target Details

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Products

ELISA Kits (11)

Antibodies (3)

Type

Competitive EIA (1)

Primary (3)

Sandwich (10)

Target

IgE (14)

Reactivity

Human (4)

Mouse (2)

Rat (1)

Canine (1)

Guinea pig (2)

Monkey (1)

Pig (2)

Rabbit (1)

Application

IHC (1)

WB (1)

ELISA (2)

Host

mouse (3)

Clonality

monoclonal mc (3)

Clone

4F4cc (3)

Format

96-Well Strip Plate (11)

Biotin Conjugated (1)

HRP Conjugated (1)

Unconjugated (1)

Publications

No (14)

Sample Type

Plasma (10)

Serum (10)

Tissue Homogenates (6)

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Rabbit IgE (Sandwich ELISA) ELISA Kit - LS-F55229

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rabbit

Range:

15.6 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$856

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Pig IgE (Competitive EIA) ELISA Kit - LS-F54179

Type:

Competitive EIA

Format:

96-Well Strip Plate

Reactivity:

Pig

Range:

0.49 - 12.5 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$1,100

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Canine IgE (Sandwich ELISA) ELISA Kit - LS-F36500

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Canine

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$768

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Rat IgE (Sandwich ELISA) ELISA Kit - LS-F36501

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Monkey IgE (Sandwich ELISA) ELISA Kit - LS-F36502

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

0.625 - 40 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$768

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Human IgE (Sandwich ELISA) ELISA Kit - LS-F36495

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.625 - 40 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$768

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Mouse IgE (Sandwich ELISA) ELISA Kit - LS-F36496

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

3.125 - 200 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Guinea pig IgE (Sandwich ELISA) ELISA Kit - LS-F36497

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Guinea pig

Range:

1.563 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$768

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IgE Antibody (clone 4F4cc, Biotin) LS-C768224

Antibody:

IgE Mouse anti-Human Monoclonal (Biotin) (4F4cc) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

60 µl/$242; 120 µl/$268; 500 µl/$397

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IgE Antibody (clone 4F4cc) LS-C768226

Antibody:

IgE Mouse anti-Human Monoclonal (4F4cc) Antibody

Reactivity:

Human

Format:

Unconjugated

Price:

60 µl/$241; 120 µl/$265; 500 µl/$382

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IgE Antibody (clone 4F4cc, HRP) LS-C768225

Antibody:

IgE Mouse anti-Human Monoclonal (HRP) (4F4cc) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

HRP Conjugated

Price:

60 µl/$242; 120 µl/$268; 500 µl/$397

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Guinea pig IgE (Sandwich ELISA) ELISA Kit - LS-F44912

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Guinea pig

Range:

1.563 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$627

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Mouse IgE (Sandwich ELISA) ELISA Kit - LS-F53169

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

1.56 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$958

Select

Pig IgE (Sandwich ELISA) ELISA Kit - LS-F4973

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Pig

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$889

Viewing 1-14 of 14 product results

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