Chicken IFN Gamma / Interferon Gamma
IFNG | IFG | Immune interferon | IFI | Interferon gamma | IFN-gamma | Interferon, gamma | IFNY
(tested or 100% immunogen sequence identity)
Recombinant chicken Interferon Gamma.
Recognizes chicken Interferon gamma (chIFN-gamma). There are at least three distinct chicken interferon proteins, designated as chIFN-alpha, chIFN-beta and chIFN-gamma. chIFN-gamma was first identified, when supernatant from chicken spleen cells stimulated with Concanavalin A (ConA ), displayed macrophage-activating factor (MAF) activity - the principle function of mammalian type II IFN-gamma. Cloning of IFN-gamma cDNA from activated chicken T cells indicates that recombinant chicken IFN-gamma activates macrophages, strongly upregulating the expression of MHC class II and iNOS genes. An be used to neutralize chIFN-gamma activity and to discriminate the antiviral activity of chIFN-gamma from that of chIFN-alpha and chIFN-beta.