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Catalog Number Size Price
LS-C743971-100 100 µg $800 
Antibody

Monoclonal Mouse anti‑Human ICAM‑1 / CD54 Antibody (IHC) LS‑C743971

Monoclonal Mouse anti‑Human ICAM‑1 / CD54 Antibody (IHC) LS‑C743971

Antibody:
ICAM-1 / CD54 Mouse anti-Human Monoclonal Antibody
Application:
IHC-P, IHC-Fr
Reactivity:
Human
Format:
Unconjugated, Unmodified
Price
Catalog Number
$800
LS-C743971-100
Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
ICAM-1 / CD54 Mouse anti-Human Monoclonal Antibody
Application:
IHC-P, IHC-Fr
Reactivity:
Human
Format:
Unconjugated, Unmodified

Specifications

Description
CD54 antibody LS-C743971 is an unconjugated mouse monoclonal antibody to human CD54 (ICAM-1). Validated for IHC.
Target
Human ICAM-1 / CD54
Synonyms
ICAM1 | BB2 | CD54 antigen | CD54 | ICAM-1 | p3.58
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG2a Monoclonal
Conjugations
Unconjugated
Modifications
Unmodified
Immunogen
Cultivated human endothelial cells
Applications
  • IHC - Paraffin (2 µg/ml)
  • IHC - Frozen
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Usage
Formaldehyde-fixed tissue slices are preferably pre-treated with proteinase K. Monoclonal antibody 1304 detects CD54 (ICAM-1) and is useful for the detection of activated endothelial cells and other activated haematopoietic cells. The antibody inhibits the binding of natural killer (NK) cells to target cells (K562). Intercellular adhesion molecule (ICAM) 1 or CD54 was initially identified with monoclonal antibody RR1/1 as a widely distributed, cytokine-inducible counter-receptor for lymphocyte-function-associated antigen (LFA) 1 (CD11a/CD18). Granulomas (macrophages/epitheloid cells) in inflamed colon from Crohn's disease and follicular dendritic cells in the tonsil from chronic tonsillitis are strongly positive for CD54 antigen. Also, CD54 is found on activated CD56+/CD3- NK cells. Human CD54, the antibody detects an epitope in domain 1 of the 95 kDa transmembrane protein..
Presentation
Lyophilized from PBS, pH 7.2, BSA, 0.01% Thimerosal.
Reconstitution
Reconstitute with 0.5 ml distilled H2O.
Storage
Store at 2°C to 8°C.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About ICAM-1 / CD54
P05362 NM_000201 NP_000192.2

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Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 1/19/2022