HTR6 / 5-HT6 Receptor

5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled

5-HT6, a Serotonin Receptor, appears to regulate cholinergic neurotransmission in the brain rather than the expected interaction as a modulator of dopaminergic transmission. This interaction predicts a possible role for 5-HT6 Receptor antagonists in the treatment of learning and memory disorders. The 5-HT6 Receptor is abundant in limbic areas, which participate in the control of mood and emotion. Some antidepressants and antipsychotics are potent 5-HT6 Receptor antagonists, making this gene valuable for the pharmaceutical industry. 5-HT6 may be involved in the pathogenesis of mood disorders, schizophrenia, in Alzheimer's disease. A splice variant that has a 289bp deletion in the transmembrane region IV and the third intracellular loop has been isolated.

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Products

Antibodies (7)

Proteins (2)

Type

Over-Expression Lysate (2)

Primary (7)

Target

HTR6 / 5-HT6 Receptor (9)

Reactivity

Human (7)

Mouse (4)

Rat (5)

Dog (1)

Hamster (1)

Horse (1)

Monkey (1)

Application

IHC (2)

IHC-P (2)

WB (4)

ELISA (2)

IF (1)

IP (1)

Peptide-ELISA (2)

Host

rabbit (7)

Product Group

GPCR Database Antibodies (2)

PathPlus Neuro (2)

Isotype

IgG (5)

Clonality

polyclonal pc (7)

Format

Unconjugated (7)

Epitope

C-Terminus (2)

190-270 aa, Internal (1)

aa1-50 (1)

aa196-245 (1)

Publications

No (9)

Tag

Myc-DDK (Flag) (2)

Species

Human (1)

Source

293T Cells (1)

HEK 293 Cells (1)

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PathPlus™ HTR6 / 5-HT6 Receptor Antibody (C-Terminus) LS-A650

Neuroscience

Fast Shipping

(5.0) Rating

Antibody:

HTR6 / 5-HT6 Receptor Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$440

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PathPlus™ HTR6 / 5-HT6 Receptor Antibody (C-Terminus) LS-A652

Neuroscience

Fast Shipping

(5.0) Rating

Antibody:

HTR6 / 5-HT6 Receptor Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Dog, Rat, Hamster, Horse, Human, Monkey

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$440

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HTR6 / 5-HT6 Receptor Antibody (aa1-50) LS-C291041

Antibody:

HTR6 / 5-HT6 Receptor Rabbit anti-Human Polyclonal (aa1-50) Antibody

Reactivity:

Human

Applications:

IP

Format:

Unconjugated

Price:

10 µg/$295; 100 µl/$514

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HTR6 / 5-HT6 Receptor Antibody (aa196-245) LS-C200063

Antibody:

HTR6 / 5-HT6 Receptor Rabbit anti-Human Polyclonal (aa196-245) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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HTR6 / 5-HT6 Receptor Antibody LS-C804618

Antibody:

HTR6 / 5-HT6 Receptor Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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HTR6 / 5-HT6 Receptor Antibody (190-270 aa, Internal) LS-C386172

Antibody:

HTR6 / 5-HT6 Receptor Rabbit anti-Human Polyclonal (190-270 aa, Internal) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

HTR6 / 5-HT6 Receptor Antibody LS-C742611

Antibody:

HTR6 / 5-HT6 Receptor Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

Select

HTR6 / 5-HT6 Receptor Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99192

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

46.8 kDa

Price:

100 µg/$494

Select

Human HTR6 / 5-HT6 Receptor Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G74143

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

46.8 kDa

Price:

20 µg/$150

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