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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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HSD11B1 / HSD11B Antibody (aa16‑33) LS‑C343882
Note: This antibody replaces LS-C388605
HSD11B antibody LS-C343882 is an unconjugated rabbit polyclonal antibody to HSD11B (HSD11B1) from human, mouse, rat and other species. Validated for IHC and WB.
Catalog
Size
Price
LS-C343882-100
100 µg (0.5 mg/ml)
$355

Popular HSD11B1 / HSD11B Products

Anti-HSD11B1 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1597 concentration 5 ug/ml.
Species: Human, Monkey, Mouse, Rat, Hamster
Applications: IHC, IHC - Paraffin, Western blot
Antibody
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, IHC - Frozen, ICC, Western blot
Antibody (0.3 ug/ml) staining of Human Liver lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Species: Human
Applications: Western blot, Peptide Enzyme-Linked Immunosorbent Assay
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Species: Human, Mouse, Rat
Applications: Immunoprecipitation
Anti-HSD11B1 / HSD11B antibody IHC staining of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Species: Human, Sheep
Applications: IHC, IHC - Paraffin, IHC - Frozen, ICC, Western blot

Product Description

HSD11B antibody LS-C343882 is an unconjugated rabbit polyclonal antibody to HSD11B (HSD11B1) from human, mouse, rat and other species. Validated for IHC and WB.
About HSD11B1 / HSD11B
HSD11B1 / HSD11B is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. P28845 NM_005525 NP_005516.1

HSD11B1 Antibody, 11-beta-HSD1 Antibody, 11-DH Antibody, CORTRD2 Antibody, HSD11B Antibody, HSD11L Antibody, SDR26C1 Antibody, HDL Antibody, HSD11 Antibody


Specifications

Target
Human HSD11B1 / HSD11B
Host
Rabbit
Reactivity
Human, Chimpanzee, Mouse, Rat (tested or 100% immunogen sequence identity)
Predicted
Bovine (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunogen affinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin
  • Western blot
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human HSD11B1(16-33aa MAYYYYSANEEFRPEMLQ), different from the related mouse sequence by two amino acids, and from the related rat sequence by four amino acids.
Epitope
aa16-33
Specificity
Widely expressed. Highest expression in liver.
Presentation
Contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2 HPO4, 0.05 mg Thimerosal, 0.05 mg sodium azide per 100 ug antibody.
Reconstitution
200 µl Distilled water
Storage
At -20°C for 1 year. After reconstitution, at 4°C for 1 month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images

Western blot

HSD11B1 antibody Western blot. All lanes: All lanes: Anti HSD11B1 at 0.5 ug/ml. Lane 1: Rat Liver Tissue Lysate at 50 ug. Lane 2: Rat Testis Tissue Lysate at 50 ug. Lane 3: SMMC Whole Cell Lysate at 40 ug. Lane 4: RAJI Whole Cell Lysate at 40 ug. Lane 5: SW620 Whole Cell Lysate at 40 ug. Predicted band size: 32 kD. Observed band size: 32 kD.
HSD11B1 antibody Western blot. All lanes: All lanes: Anti HSD11B1 at 0.5 ug/ml. Lane 1: Rat Liver Tissue Lysate at 50 ug. Lane 2: Rat Testis Tissue Lysate at 50 ug. Lane 3: SMMC Whole Cell Lysate at 40 ug. Lane 4: RAJI Whole Cell Lysate at 40 ug. Lane 5: SW620 Whole Cell Lysate at 40 ug. Predicted band size: 32 kD. Observed band size: 32 kD.

Western blot

HSD11B1 antibody Western blot. All lanes: All lanes: Anti HSD11B1 at 0.5 ug/ml. Lane 1: Rat Liver Tissue Lysate at 50 ug. Lane 2: Rat Testis Tissue Lysate at 50 ug. Lane 3: SMMC Whole Cell Lysate at 40 ug. Lane 4: RAJI Whole Cell Lysate at 40 ug. Lane 5: SW620 Whole Cell Lysate at 40 ug. Predicted band size: 32 kD. Observed band size: 32 kD.
HSD11B1 antibody Western blot. All lanes: All lanes: Anti HSD11B1 at 0.5 ug/ml. Lane 1: Rat Liver Tissue Lysate at 50 ug. Lane 2: Rat Testis Tissue Lysate at 50 ug. Lane 3: SMMC Whole Cell Lysate at 40 ug. Lane 4: RAJI Whole Cell Lysate at 40 ug. Lane 5: SW620 Whole Cell Lysate at 40 ug. Predicted band size: 32 kD. Observed band size: 32 kD.

Western blot

HSD11B1 antibody Western blot. All lanes: All lanes: Anti HSD11B1 at 0.5 ug/ml. Lane 1: Rat Liver Tissue Lysate at 50 ug. Lane 2: Rat Testis Tissue Lysate at 50 ug. Lane 3: SMMC Whole Cell Lysate at 40 ug. Lane 4: RAJI Whole Cell Lysate at 40 ug. Lane 5: SW620 Whole Cell Lysate at 40 ug. Predicted band size: 32 kD. Observed band size: 32 kD.
HSD11B1 antibody Western blot. All lanes: All lanes: Anti HSD11B1 at 0.5 ug/ml. Lane 1: Rat Liver Tissue Lysate at 50 ug. Lane 2: Rat Testis Tissue Lysate at 50 ug. Lane 3: SMMC Whole Cell Lysate at 40 ug. Lane 4: RAJI Whole Cell Lysate at 40 ug. Lane 5: SW620 Whole Cell Lysate at 40 ug. Predicted band size: 32 kD. Observed band size: 32 kD.

Western blot

HSD11B1 antibody Western blot. All lanes: All lanes: Anti HSD11B1 at 0.5 ug/ml. Lane 1: Rat Liver Tissue Lysate at 50 ug. Lane 2: Rat Testis Tissue Lysate at 50 ug. Lane 3: SMMC Whole Cell Lysate at 40 ug. Lane 4: RAJI Whole Cell Lysate at 40 ug. Lane 5: SW620 Whole Cell Lysate at 40 ug. Predicted band size: 32 kD. Observed band size: 32 kD.
HSD11B1 antibody Western blot. All lanes: All lanes: Anti HSD11B1 at 0.5 ug/ml. Lane 1: Rat Liver Tissue Lysate at 50 ug. Lane 2: Rat Testis Tissue Lysate at 50 ug. Lane 3: SMMC Whole Cell Lysate at 40 ug. Lane 4: RAJI Whole Cell Lysate at 40 ug. Lane 5: SW620 Whole Cell Lysate at 40 ug. Predicted band size: 32 kD. Observed band size: 32 kD.

Requested From: United States
Date Requested: 8/19/2018

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