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HSD11B1 / HSD11B
hydroxysteroid (11-beta) dehydrogenase 1
HSD11B1 / HSD11B is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Mutations in this gene and H6PD (hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)) are the cause of cortisone reductase deficiency. Alternate splicing results in multiple transcript variants encoding the same protein.
| Gene Name: | hydroxysteroid (11-beta) dehydrogenase 1 |
| Synonyms: | HSD11B1, 11-beta-HSD1, 11-DH, CORTRD2, HSD11B, HSD11L, SDR26C1, HDL, HSD11 |
| Target Sequences: | NM_005525 NP_005516.1 P28845 |
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HSD11B1 / HSD11B Rabbit anti-Human Polyclonal (aa77-92) Antibody
Mouse, Rat, Hamster, Human, Monkey
IHC, IHC-P, WB
Unconjugated
1 Each/$485
HEK 293 Cells
Myc-DDK (Flag)
32.2 kDa
20 µg/$1,107
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
E. coli
His-SUMO
45.5 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$768
Sandwich
96-Well Strip Plate
Human
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$834
HSD11B1 / HSD11B Rabbit anti-Human Polyclonal (aa131-145) Antibody
Mouse, Rat, Human
ICC, IHC, IHC-Fr, IHC-P, WB
Unconjugated
100 µg/$380
HSD11B1 / HSD11B Goat anti-Human Polyclonal (aa282-292) Antibody
Human
Peptide-ELISA, WB
Unconjugated
100 µg/$503
HSD11B1 / HSD11B Rabbit anti-Human Polyclonal (aa232-292) Antibody
Sheep, Human
ICC, IHC, IHC-Fr, IHC-P, WB
Unconjugated
50 µl/$460
HSD11B1 / HSD11B Rabbit anti-Human Polyclonal (aa1-50) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
100 µl/$515
HSD11B1 / HSD11B Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
HSD11B1 / HSD11B Rabbit anti-Human Polyclonal (aa25-292) Antibody
Mouse, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
HSD11B1 / HSD11B Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
HSD11B1 / HSD11B Rabbit anti-Human Polyclonal (aa25-292) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
HSD11B1 / HSD11B Rabbit anti-Human Polyclonal (aa25-292) (HRP) Antibody
Human
ELISA, IHC, IHC-P, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
HSD11B1 / HSD11B Rabbit anti-Human Polyclonal (aa25-292) (Biotin) Antibody
Human
ELISA, IHC, IHC-P, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
HSD11B1 / HSD11B Rabbit anti-Human Polyclonal (aa25-292) (FITC) Antibody
Human
ELISA, IHC, IHC-P, WB
FITC Conjugated
50 µg/$294; 100 µg/$360
HSD11B1 / HSD11B Rabbit anti-Human Polyclonal (aa131-145) (Sepharose) Antibody
Mouse, Rat, Human
IP
Sepharose Conjugated
100 µg/$399
HSD11B1 / HSD11B Rabbit anti-Human Polyclonal (1-50 aa, N-terminal) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
HEK 293 Cells
Myc-DDK (Flag)
32.2 kDa
20 µg/$1,107
HSD11B1 / HSD11B Rabbit anti-Human Polyclonal (aa25-292) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
HSD11B1 / HSD11B Rabbit anti-Human Polyclonal (aa16-33) Antibody
Mouse, Rat, Chimpanzee, Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
HSD11B1 / HSD11B Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100 µg/$357
HSD11B1 / HSD11B Mouse anti-Human Monoclonal (2C10) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$423
HSD11B1 / HSD11B Rabbit anti-Human Polyclonal (aa33-82) Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
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product results
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