Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
HOXA9 antibody was raised against synthetic peptide PDFSPCSFQSKA from an internal region of human HOXA9 (NP_689952.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Baboon, Monkey, Galago, Marmoset, Mouse, Rat, Shrew, Panda, Bovine, Bat, Dog, Rabbit, Horse (100%); Hamster, Platypus (92%); Xenopus (83%).
LS-E27368 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C113018. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Peptide ELISA: antibody detection limit dilution 1:8000. Western blot: Preliminary experiments gave an approx 22kDa band in Human Colon, Lymph Node and Uterus lysates after 1 ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 30.2kDa according to NP_689952.1. The 22kDa band was successfully blocked by incubation with the immunizing peptide.
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation.