HLA-DRB3

Major Histocompatibility Complex, Class II, Dr Beta 3

HLA-DRB3 belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DRA) and a beta (DRB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. DRB1 is expressed at a level five times higher than its paralogues DRB3, DRB4 and DRB5. The presence of DRB3 is linked with allelic variants of DRB1, otherwise it is omitted. There are 4 related pseudogenes: DRB2, DRB6, DRB7, DRB8 and DRB9.

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Products

Antibodies (22)

Proteins (11)

ELISA Kits (1)

Type

Over-Expression Lysate (10)

Primary (22)

Recombinant (1)

Sandwich (1)

Target

HLA-DRB3 (34)

Reactivity

Human (23)

Mouse (3)

Rat (4)

Monkey (3)

Application

IHC (5)

WB (16)

Flo (1)

ELISA (2)

ICC (1)

IF (2)

Peptide-ELISA (1)

Host

rabbit (21)

mouse (1)

Isotype

IgG (17)

Clonality

polyclonal pc (22)

Format

96-Well Strip Plate (1)

APC Conjugated (1)

Biotin Conjugated (3)

FITC Conjugated (3)

HRP Conjugated (3)

PE Conjugated (1)

Unconjugated (11)

Epitope

aa150-199 (4)

aa4-266 (1)

Publications

No (34)

Sample Type

Cell Supernatant (1)

Plasma (1)

Serum (1)

Tag

GST (1)

Myc-DDK (Flag) (10)

Species

Human (2)

Source

293T Cells (1)

HEK 293 Cells (9)

Wheat Germ Extract (1)

Purification

Purified (1)

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HLA-DRB3 Antibody LS-C809529

Antibody:

HLA-DRB3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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HLA-DRB3 Antibody LS-C331580

Antibody:

HLA-DRB3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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HLA-DRB3 Antibody LS-C673266

Antibody:

HLA-DRB3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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HLA-DRB3 Antibody (HRP) LS-C673265

Antibody:

HLA-DRB3 Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

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HLA-DRB3 Antibody (Biotin) LS-C673268

Antibody:

HLA-DRB3 Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

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HLA-DRB3 Antibody (FITC) LS-C673267

Antibody:

HLA-DRB3 Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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HLA-DRB3 Antibody LS-C830146

Antibody:

HLA-DRB3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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HLA-DRB3 Antibody LS-C192792

Antibody:

HLA-DRB3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

50 µl/$356; 100 µl/$461

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HLA-DRB3 Antibody LS-C833681

Antibody:

HLA-DRB3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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HLA-DRB3 Antibody LS-C308262

Antibody:

HLA-DRB3 Mouse anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

Flo, WB

Format:

Unconjugated

Price:

50 µg/$705

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HLA-DRB3 Antibody (aa4-266) LS-C185683

Antibody:

HLA-DRB3 Rabbit anti-Human Polyclonal (aa4-266) Antibody

Reactivity:

Human

Applications:

ICC

Format:

Unconjugated

Price:

100 µl/$450

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HLA-DRB3 Antibody LS-C311225

Antibody:

HLA-DRB3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$749

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HLA-DRB3 Antibody (HRP) LS-C542530

Antibody:

HLA-DRB3 Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$937

Select

HLA-DRB3 Antibody (Biotin) LS-C522400

Antibody:

HLA-DRB3 Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$937

Select

HLA-DRB3 Antibody (FITC) LS-C532443

Antibody:

HLA-DRB3 Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$937

Select

HLA-DRB3 Antibody (PE) LS-C650644

Antibody:

HLA-DRB3 Rabbit anti-Human Polyclonal (PE) Antibody

Reactivity:

Human

Applications:

WB

Format:

PE Conjugated

Price:

100 µl/$937

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HLA-DRB3 Antibody (APC) LS-C514183

Antibody:

HLA-DRB3 Rabbit anti-Human Polyclonal (APC) Antibody

Reactivity:

Human

Applications:

WB

Format:

APC Conjugated

Price:

100 µl/$937

• Unconjugated
• HRP
• Biotin
• FITC
• PE
• APC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • PE
  • APC

Select

HLA-DRB3 Antibody (aa150-199) LS-C146376

Antibody:

HLA-DRB3 Rabbit anti-Human Polyclonal (aa150-199) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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HLA-DRB3 Antibody (aa150-199, HRP) LS-C471081

Antibody:

HLA-DRB3 Rabbit anti-Human Polyclonal (aa150-199) (HRP) Antibody

Reactivity:

Human, Monkey

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

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HLA-DRB3 Antibody (aa150-199, Biotin) LS-C471079

Antibody:

HLA-DRB3 Rabbit anti-Human Polyclonal (aa150-199) (Biotin) Antibody

Reactivity:

Human, Monkey

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

HLA-DRB3 Antibody (aa150-199, FITC) LS-C471080

Antibody:

HLA-DRB3 Rabbit anti-Human Polyclonal (aa150-199) (FITC) Antibody

Reactivity:

Human, Monkey

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

HLA-DRB3 Antibody LS-C747547

Antibody:

HLA-DRB3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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Human HLA-DRB3 (Sandwich ELISA) ELISA Kit - LS-F74878

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

6.25 - 400 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Supernatant, Plasma, Serum

Price:

1 Plate/$598

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Human HLA-DRB3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G87995

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

27 kDa

Price:

20 µg/$150

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Human HLA-DRB3 Protein (Recombinant GST) (Full Length) - LS-G28841

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

55 kDa

Price:

10 µg/$479; 25 µg/$670

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