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Catalog Number Size Price
LS-C390300-100 100 µg (1 mg/ml) $522 
Antibody

Monoclonal Mouse anti‑Human HLA‑DQ Antibody (clone SPV‑L3, Azide‑free,BSA‑free, IF) LS‑C390300

Monoclonal Mouse anti‑Human HLA‑DQ Antibody (clone SPV‑L3, Azide‑free,BSA‑free, IF) LS‑C390300

Antibody:
HLA-DQ Mouse anti-Human Monoclonal (Azide-free, BSA-free) (SPV-L3) Antibody
Application:
IF, Flo
Reactivity:
Human
Format:
Unconjugated, Azide-free, BSA-free
Other formats:
Price
Catalog Number
$522
LS-C390300-100
Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
HLA-DQ Mouse anti-Human Monoclonal (Azide-free, BSA-free) (SPV-L3) Antibody
Application:
IF, Flo
Reactivity:
Human
Format:
Unconjugated, Azide-free, BSA-free
Other formats:

Specifications

Description
HLA-DQ antibody LS-C390300 is an unconjugated mouse monoclonal antibody to human HLA-DQ. Validated for Flow and IF.
Target
Human HLA-DQ
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG2a,k Monoclonal
Clone
SPV-L3
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Azide-free, BSA-free. Also available Unmodified.
Immunogen
The T4-positive CTL clone HG-38.
Specificity
Human HLA-DQ
Applications
  • Immunofluorescence (0.5 - 1 µg/ml)
  • Flow Cytometry (0.5 - 1 µg/10E6 cells)
Usage
The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. Recognizes a DQ antigen, which is a dimer of 60kDa. The class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B Lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35kDa. It is encoded by 5 exons. exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to four different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation. Optimal dilution of the HLA-DQ antibody should be determined by the researcher.
Presentation
1X PBS, pH 7.4; BSA free, sodium azide free
Storage
Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee

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Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 9/24/2021