HLA-A

Major Histocompatibility Complex, Class I, A Heavy Chain

HLA-A belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-A alleles have been described.

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Products

Antibodies (83)

Proteins (7)

ELISA Kits (4)

Type

Over-Expression Lysate (3)

Primary (83)

Recombinant (4)

Sandwich (3)

Sandwich CLIA (1)

Target

HLA-A (94)

Reactivity

Human (78)

Mouse (14)

Rat (6)

Monkey (1)

Rabbit (4)

Application

IHC (13)

IHC-Fr (3)

IHC-P (9)

WB (39)

Flo (45)

Ctox (26)

ELISA (10)

Func (1)

ICC (3)

IE (2)

IF (16)

IP (6)

Peptide-ELISA (3)

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Host

rabbit (23)

mouse (56)

guinea pig (4)

Product Group

IHCPlus (3)

Isotype

IgG (20)

IgG1 (8)

IgG1,k (2)

IgG2a (5)

IgG2a,k (1)

IgG2b (5)

IgM (32)

Clonality

monoclonal mc (55)

polyclonal pc (28)

Clone

108-2C5 (2)

2D6 (1)

7G7F9 (3)

BB7.2 (1)

HC10 (1)

HCA2 (1)

Format

12 x 8-Well Microstrips (1)

96-Well Microplate (1)

96-Well Strip Plate (2)

APC Conjugated (2)

Azide-free (2)

Biotin Conjugated (12)

BSA-free (1)

FITC Conjugated (7)

HRP Conjugated (3)

PE Conjugated (2)

Unconjugated (57)

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Epitope

aa70-99 (7)

aa62-111 (4)

C-Terminus (1)

aa82-106 (1)

Publications

No (94)

Sample Type

Plasma (3)

Serum (3)

Tissue Homogenates (2)

Tag

6His, N-terminus (1)

GST (1)

His, N-Terminal (2)

Myc-DDK (Flag) (3)

Species

Human (6)

Source

293T Cells (1)

E. coli (2)

HEK 293 Cells (3)

Wheat Germ Extract (1)

Purification

Purified (3)

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IHC-plus™ HLA-A Antibody (aa70-99) LS-B10658

(4.0) Rating

Antibody:

HLA-A Mouse anti-Human Monoclonal (aa70-99) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

200 µl/$440

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IHC-plus™ HLA-A Antibody LS-B10898

(4.0) Rating

Antibody:

HLA-A Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

50 µl/$460

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HLA-A Antibody (FITC) LS-C24443

Antibody:

HLA-A Mouse anti-Human Monoclonal (FITC) Antibody

Reactivity:

Human

Applications:

Flo

Format:

FITC Conjugated

Price:

250 µl/$1,203

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HLA-A Antibody LS-C24453

Antibody:

HLA-A Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

Ctox

Format:

Unconjugated

Price:

100 µl/$1,295

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HLA-A Antibody (clone 108-2C5, Azide-free, BSA-free) LS-C390307

Antibody:

HLA-A Mouse anti-Human Monoclonal (Azide-free, BSA-free) (108-2C5) Antibody

Reactivity:

Human

Applications:

Flo, IF

Format:

Unconjugated, Azide-free, BSA-free

Price:

100 µg/$574

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Human HLA-A Protein (Recombinant 6His, N-terminus) - LS-G137222

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

36.7 kDa

Price:

1 mg/$1,679; 100 µg/$598; 20 µg/$405

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HLA-A Antibody (clone HC10) LS-C828416

Antibody:

HLA-A Mouse anti-Human Monoclonal (HC10) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, ICC, IE, IHC-Fr, IHC-P, IP, WB

Format:

Unconjugated

Price:

0.1 mg/$424

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HLA-A Antibody (Biotin) LS-C24460

Antibody:

HLA-A Mouse anti-Human Monoclonal (Biotin) Antibody

Reactivity:

Human

Applications:

Flo, IF

Format:

Biotin Conjugated

Price:

250 µl/$1,321

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HLA-A Antibody (Biotin) LS-C24430

Antibody:

HLA-A Mouse anti-Human Monoclonal (Biotin) Antibody

Reactivity:

Human

Applications:

Ctox, Flo, IF

Format:

Biotin Conjugated

Price:

250 µl/$1,312

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HLA-A Antibody (Biotin) LS-C24450

Antibody:

HLA-A Mouse anti-Human Monoclonal (Biotin) Antibody

Reactivity:

Human

Applications:

Flo

Format:

Biotin Conjugated

Price:

50 µl/$478; 100 µl/$748; 250 µl/$1,388

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HLA-A Antibody LS-C482358

Antibody:

HLA-A Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ICC, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$286; 100 µl/$321; 200 µl/$386

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HLA-A Antibody LS-C804392

Antibody:

HLA-A Rabbit anti-Human Polyclonal Antibody

Reactivity:

Rat, Human, Monkey

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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HLA-A Antibody (clone HCA2) LS-C828417

Antibody:

HLA-A Mouse anti-Human Monoclonal (HCA2) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, ICC, IE, IHC-Fr, IHC-P, IP, WB

Format:

Unconjugated

Price:

0.1 mg/$424

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Human HLA-A (Sandwich ELISA) ELISA Kit - LS-F9160

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Tissue Homogenates

Price:

1 Plate/$834

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IHC-plus™ HLA-A Antibody LS-B13866

(4.0) Rating

Antibody:

HLA-A Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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HLA-A Antibody LS-C24459

Antibody:

HLA-A Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

Flo, IF

Format:

Unconjugated

Price:

100 µl/$1,321

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HLA-A Antibody (clone 2D6) LS-C197413

Antibody:

HLA-A Mouse anti-Human Monoclonal (2D6) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$423

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HLA-A Antibody (Biotin) LS-C24462

Antibody:

HLA-A Mouse anti-Human Monoclonal (Biotin) Antibody

Reactivity:

Human

Applications:

Flo, IF

Format:

Biotin Conjugated

Price:

250 µl/$1,321

Select

HLA-A Antibody (Biotin) LS-C24417

Antibody:

HLA-A Mouse anti-Human Monoclonal (Biotin) Antibody

Reactivity:

Human

Applications:

Flo, IF

Format:

Biotin Conjugated

Price:

50 µl/$518; 100 µl/$709; 250 µl/$1,355

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HLA-A Antibody LS-C24433

Antibody:

HLA-A Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

Ctox, Flo

Format:

Unconjugated

Price:

100 µl/$1,321

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HLA-A Antibody LS-C660292

Antibody:

HLA-A Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IF, IHC, IP, WB

Format:

Unconjugated

Price:

100 µg/$351

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HLA-A Antibody (aa62-111, FITC) LS-C470059

Antibody:

HLA-A Rabbit anti-Human Polyclonal (aa62-111) (FITC) Antibody

Reactivity:

Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

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HLA-A Antibody (clone BB7.2) LS-C123772

Antibody:

HLA-A Mouse anti-Human Monoclonal (BB7.2 ) Antibody

Reactivity:

Human

Applications:

Flo, Func, IHC, IHC-Fr, IP

Format:

Unconjugated

Price:

500 µg/$968

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Human HLA-A Protein (Recombinant His, N-Terminal) (Gly25-Ile308) - LS-G96947

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

37 kDa

Price:

10 µg/$265; 200 µg/$484; 50 µg/$315

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Human HLA-A Protein (Over-Expression Lysate His, N-Terminal) (Gly25-Ile308) - LS-G96949

Source:

HEK 293 Cells

Tag:

His, N-Terminal

Molecular Weight:

~33 kDa

Price:

100 µg/$298

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