Reactivity
Human, Mouse, Chicken, Xenopus, Zebrafish, Drosophila
(tested or 100% immunogen sequence identity)
Immunogen
A synthetic peptide containing phospho serine at position 28 CARKS*APATGGVKK, of human Histone H3. The immunogen sequence (CARKS*APATGGVKK) is conserved across mammalian and invertebrates, as well as plants. Percent identity by BLAST analysis: Human, Mouse, Chicken, Xenopus, Zebrafish, Drosophila, Rice, Arabidopsis (100%).
Specificity
In anti-Fas mAb treated Jurkat, an 18 kD band is observed.