HEXB

hexosaminidase B (beta polypeptide)

Hexosaminidase B is the beta subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Beta subunit gene mutations lead to Sandhoff disease (GM2-gangliosidosis type II). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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Products

Antibodies (59)

ELISA Kits (14)

Proteins (10)

Type

Cell-Based (1)

Custom (2)

Over-Expression Lysate (2)

Primary (59)

Recombinant (8)

Sandwich (11)

Target

HEXB (83)

Reactivity

Human (37)

Mouse (20)

Rat (15)

Pig (1)

Application

IHC (10)

IHC-P (8)

WB (52)

ELISA (5)

ICC (1)

IF (3)

Peptide-ELISA (3)

Host

rabbit (58)

mouse (1)

Product Group

PathPlus Cancer (4)

Isotype

IgG (11)

Clonality

polyclonal pc (59)

Format

96-Well Microplate (1)

96-Well Strip Plate (13)

APC (5)

APC Conjugated (5)

Biotin Conjugated (6)

Cy3 Conjugated (5)

Cy7 Conjugated (5)

FITC Conjugated (6)

HRP Conjugated (6)

PE Conjugated (5)

Unconjugated (21)

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Epitope

aa100-216 (8)

aa101-217 (8)

aa122-311 (8)

aa294-435 (8)

aa315-456 (8)

450-530 aa, C-terminal (1)

C-Terminus (1)

Ser516 (1)

aa170-203 (1)

aa381-556 (1)

aa481-530 (1)

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Publications

No (82)

Yes (1)

Sample Type

Adherent Cell Cultures (1)

Cell Culture Supernatants (1)

Plasma (11)

Serum (11)

Tissue Homogenates (8)

Urine (1)

Tag

GST (1)

His (5)

His-T7 (1)

Myc-DDK (Flag) (3)

Species

Human (5)

Mouse (3)

Rat (1)

Source

293T Cells (1)

E. coli (5)

HEK 293 Cells (2)

Human Cells (1)

Wheat Germ Extract (1)

Purification

Purified (1)

Low Endotoxin Level

Low endotoxin level (1)

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HEXB Antibody (C-Terminus) LS-C354001

(4.0) Rating

(1) Publication(s)

Antibody:

HEXB Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

ICC, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$299

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PathPlus™ HEXB Antibody (aa294-435) LS-B16803

Cancer

(5.0) Rating

Antibody:

HEXB Rabbit anti-Mouse Polyclonal (aa294-435) Antibody

Reactivity:

Mouse

Applications:

IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$460

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HEXB Antibody (aa294-435, Biotin) LS-C299857

Antibody:

HEXB Rabbit anti-Mouse Polyclonal (aa294-435) (Biotin) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$311; 200 µl/$353; 500 µl/$496; 1 ml/$567; 2 ml/$769; 5 ml/$1,248

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HEXB Antibody (aa294-435, FITC) LS-C304741

Antibody:

HEXB Rabbit anti-Mouse Polyclonal (aa294-435) (FITC) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$338; 200 µl/$392; 500 µl/$573; 1 ml/$698; 2 ml/$936; 5 ml/$1,588

• Unconjugated
• Biotin
• FITC

• Unconjugated
• Biotin
• FITC

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PathPlus™ HEXB Antibody (aa481-530) LS-B8401

Cancer

(5.0) Rating

Antibody:

HEXB Rabbit anti-Human Polyclonal (aa481-530) Antibody

Reactivity:

Human

Applications:

IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$440

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HEXB Antibody (aa101-217) LS-C294500

Antibody:

HEXB Rabbit anti-Mouse Polyclonal (aa101-217) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$301; 200 µl/$340; 500 µl/$470; 1 ml/$535; 2 ml/$698; 5 ml/$1,161

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HEXB Antibody (aa101-217, Biotin) LS-C684829

Antibody:

HEXB Rabbit anti-Mouse Polyclonal (aa101-217) (Biotin) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$311; 200 µl/$353; 500 µl/$496; 1 ml/$567; 2 ml/$769; 5 ml/$1,248

• Unconjugated
• Biotin

• Unconjugated
• Biotin

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Human HEXB (Sandwich ELISA) ELISA Kit - LS-F4376

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$764

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PathPlus™ HEXB Antibody LS-A10968

Cancer

Fast Shipping

(5.0) Rating

Antibody:

HEXB Rabbit anti-Human Polyclonal Antibody

Applications:

IHC-P

Format:

Unconjugated

Price:

50 µg/$460

Select

Mouse HEXB (Sandwich ELISA) ELISA Kit - LS-F56322

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$768

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Mouse HEXB (Sandwich ELISA) ELISA Kit - LS-F4378

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$782

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Human HEXB (Sandwich ELISA) ELISA Kit - LS-F11626

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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HEXB Antibody (aa381-556) LS-C344061

Antibody:

HEXB Rabbit anti-Human Polyclonal (aa381-556) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

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HEXB Antibody (aa315-456) LS-C294496

Antibody:

HEXB Rabbit anti-Human Polyclonal (aa315-456) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$299; 200 µl/$337; 500 µl/$463; 1 ml/$527; 2 ml/$682; 5 ml/$1,141

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HEXB Antibody (aa122-311) LS-C372563

Antibody:

HEXB Rabbit anti-Human Polyclonal (aa122-311) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$299; 200 µl/$337; 500 µl/$463; 1 ml/$527; 2 ml/$682; 5 ml/$1,141

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HEXB Antibody (450-530 aa, C-terminal) LS-C383912

Antibody:

HEXB Rabbit anti-Human Polyclonal (450-530 aa, C-terminal) Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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HEXB Antibody LS-C804464

Antibody:

HEXB Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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Human HEXB Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G80748

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

62.9 kDa

Price:

20 µg/$150

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Human HEXB Protein (Recombinant His) (aa122-311) - LS-G12542

Source:

E. coli

Tag:

His

Molecular Weight:

22.9 kDa

Price:

10 µg/$285; 50 µg/$470; 100 µg/$750; 200 µg/$937; 1 mg/$2,063; 500 µg/$1,594; 5 mg/$3,277; 2 mg/$2,252

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PathPlus™ HEXB Antibody LS-A10969

Cancer

Fast Shipping

(5.0) Rating

Antibody:

HEXB Rabbit anti-Human Polyclonal Antibody

Applications:

IHC-P

Format:

Unconjugated

Price:

50 µg/$460

Select

HEXB Antibody LS-C666121

Antibody:

HEXB Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$331

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HEXB Antibody LS-C822560

Antibody:

HEXB Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$357

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HEXB Antibody LS-C486960

Antibody:

HEXB Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

100 µl/$412

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HEXB Antibody LS-C671731

Antibody:

HEXB Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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HEXB Antibody (Ser516) LS-C191934

Antibody:

HEXB Rabbit anti-Human Polyclonal (Ser516) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

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