HEXA

hexosaminidase A (alpha polypeptide)

HEXA is the alpha subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Alpha subunit gene mutations lead to Tay-Sachs disease (GM2-gangliosidosis type I).

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Products

Antibodies (63)

ELISA Kits (10)

Proteins (10)

Type

Custom (3)

Over-Expression Lysate (2)

Primary (63)

Recombinant (8)

Sandwich (7)

Target

HEXA (83)

Reactivity

Human (58)

Mouse (30)

Rat (16)

Dog (3)

Gibbon (3)

Guinea pig (3)

Monkey (4)

Orangutan (3)

Pig (11)

Application

IHC (15)

IHC-P (10)

WB (57)

Flo (4)

ELISA (20)

IF (2)

Peptide-ELISA (1)

Host

rabbit (56)

mouse (7)

Product Group

IHCPlus (3)

Isotype

IgG (30)

IgG1,k (1)

IgG2a (1)

IgG2a,l (1)

IgG2b (3)

Clonality

monoclonal mc (6)

polyclonal pc (57)

Clone

1D4B (1)

3D1 (1)

3F10 (2)

AT20F1 (1)

Format

96-Well Microplate (1)

96-Well Strip Plate (9)

APC (2)

APC Conjugated (5)

Azide-free (2)

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Cy3 Conjugated (2)

Cy7 Conjugated (2)

FITC Conjugated (7)

HRP Conjugated (7)

PE Conjugated (5)

Unconjugated (28)

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Epitope

aa318-529 (8)

aa319-528 (8)

aa142-170 (7)

aa315-343 (7)

aa431-480 (4)

121-170 aa, Internal (1)

Internal (1)

aa1-529 (1)

aa191-207 (1)

aa513-529 (1)

Publications

No (82)

Yes (1)

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Cell Culture Supernatants (1)

Plasma (7)

Serum (7)

Tissue Homogenates (3)

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GST (1)

His (3)

His, N-Terminal (1)

His-T7 (2)

Myc-DDK (Flag) (3)

Species

Human (7)

Mouse (2)

Source

293T Cells (1)

Baculovirus (2)

E. coli (4)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (4)

Low Endotoxin Level

Low endotoxin level (2)

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IHC-plus™ HEXA Antibody (aa142-170) LS-B9894

(4.0) Rating

Antibody:

HEXA Rabbit anti-Human Polyclonal (aa142-170) Antibody

Reactivity:

Mouse, Human

Applications:

Flo, IHC, IHC-P, WB

Format:

Unconjugated

Price:

200 µl/$460

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HEXA Antibody (aa431-480) LS-B6959

Antibody:

HEXA Rabbit anti-Human Polyclonal (aa431-480) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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HEXA Antibody (aa431-480, HRP) LS-C468102

Antibody:

HEXA Rabbit anti-Human Polyclonal (aa431-480) (HRP) Antibody

Reactivity:

Mouse, Dog, Guinea pig, Pig, Orangutan, Gibbon, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

100 µl/$469

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HEXA Antibody (aa431-480, Biotin) LS-C468100

Antibody:

HEXA Rabbit anti-Human Polyclonal (aa431-480) (Biotin) Antibody

Reactivity:

Mouse, Dog, Guinea pig, Pig, Orangutan, Gibbon, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

100 µl/$469

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HEXA Antibody (aa431-480, FITC) LS-C468101

Antibody:

HEXA Rabbit anti-Human Polyclonal (aa431-480) (FITC) Antibody

Reactivity:

Mouse, Dog, Guinea pig, Pig, Orangutan, Gibbon, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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HEXA Antibody (clone 3D1) LS-C197404

(4.0) Rating

(1) Publication(s)

Antibody:

HEXA Mouse anti-Human Monoclonal (3D1) Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

50 µg/$423

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IHC-plus™ HEXA Antibody (clone AT20F1) LS-B9668

(4.0) Rating

Antibody:

HEXA Mouse anti-Human Monoclonal (AT20F1) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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Human HEXA Protein (Recombinant His) - LS-G3329

Source:

Baculovirus

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Price:

50 µg/$361; 250 µg/$985; 10 µg/$261

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Human HEXA (Sandwich ELISA) ELISA Kit - LS-F7361

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$764

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HEXA Antibody (clone 3F10) LS-C169185

Antibody:

HEXA Mouse anti-Human Monoclonal (3F10) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, WB

Format:

Unconjugated

Price:

100 µl/$459

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HEXA Antibody LS-C334185

Antibody:

HEXA Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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HEXA Antibody LS-C669794

Antibody:

HEXA Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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HEXA Antibody (aa315-343) LS-C166844

Antibody:

HEXA Rabbit anti-Human Polyclonal (aa315-343) Antibody

Reactivity:

Human

Applications:

Flo, IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

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Rat HEXA (Sandwich ELISA) ELISA Kit - LS-F49285

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.31 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

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HEXA Antibody LS-C747545

Antibody:

HEXA Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

Select

HEXA Antibody (aa191-207) LS-C312933

Antibody:

HEXA Rabbit anti-Human Polyclonal (aa191-207) Antibody

Reactivity:

Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

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HEXA Antibody LS-C666120

Antibody:

HEXA Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$341

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HEXA Antibody (clone 3F10) LS-C759644

Antibody:

HEXA Mouse anti-Human Monoclonal (3F10) Antibody

Reactivity:

Mouse, Human

Applications:

Flo, WB

Format:

Unconjugated

Price:

100 µg/$503

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HEXA Antibody (aa1-529, clone 1D4B) LS-C189807

Antibody:

HEXA Mouse anti-Human Monoclonal (aa1-529) (1D4B) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

100 µg/$896

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HEXA Antibody LS-C806698

Antibody:

HEXA Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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HEXA Antibody LS-C341681

Antibody:

HEXA Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

50 µl/$338; 100 µl/$431

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HEXA Antibody LS-C667219

Antibody:

HEXA Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$361

Select

HEXA Antibody (aa315-343) LS-C327554

Antibody:

HEXA Rabbit anti-Human Polyclonal (aa315-343) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

HEXA Antibody (aa142-170) LS-C327555

Antibody:

HEXA Rabbit anti-Human Polyclonal (aa142-170) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

HEXA Antibody (121-170 aa, Internal) LS-C387001

Antibody:

HEXA Rabbit anti-Human Polyclonal (121-170 aa, Internal) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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