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HACL1

2-hydroxyacyl-CoA lyase 1

Catalyzes a carbon-carbon cleavage reaction; cleaves a 2-hydroxy-3-methylacyl-CoA into formyl-CoA and a 2-methyl-branched fatty aldehyde.

Gene Name: 2-hydroxyacyl-CoA lyase 1
Synonyms: HACL1, 2-hydroxyphytanol-CoA lyase, 2-HPCL, 2-hydroxyacyl-CoA lyase 1, 2-hydroxyphytanoyl-CoA lyase, HPCl2, PHYH2, Phytanoyl-CoA hydroxylase 2, Phytanoyl-CoA 2-hydroxylase 2, HPCL
Target Sequences: NM_012260 NP_036392.2 Q9UJ83

Publications (1)

1
Tissue Proteome of 2-Hydroxyacyl-CoA Lyase Deficient Mice Reveals Peroxisome Proliferation and Activation of ?-Oxidation. Youssef Khalil, Sara Carrino, Fujun Lin, Anna Ferlin, Heena V Lad, Francesca Mazzacuva, Sara Falcone, Natalie Rivers, Gareth Banks, Danilo Concas, Carlos Aguilar, Andrew R Haynes, Andy Blease, Thomas Nicol, Raya Al-Shawi, Wendy Heywood, Paul Potter, Kevin Mills, Daniel P Gale, Peter T Clayton. International journal of molecular sciences. 2022 January;23: [Full Text Article] [PubMed:35055171] [PMC:PMC8781152]

☰ Filters
Antibodies (15)
Proteins (4)
Over-Expression Lysate (2)
Primary (15)
Recombinant (2)
HACL1 (19)
Human (15)
Mouse (9)
Chimpanzee (3)
Gibbon (3)
Guinea pig (3)
Orangutan (3)
IHC (3)
IHC-P (2)
WB (15)
ELISA (7)
IF (1)
IP (1)
rabbit (14)
mouse (1)
Product Group
IHCPlus (1)
IgG (10)
polyclonal pc (15)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Unconjugated (7)
aa550-578 (7)
aa102-151 (4)
aa528-578 (1)
No (19)
GST (1)
Myc-DDK (Flag) (3)
Human (3)
293T Cells (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (1)
HACL1 Antibody - Anti-HACL1 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5 ug/ml.
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HACL1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
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HACL1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$341
HACL1 Antibody - Formalin-fixed and paraffin-embedded human skeletal muscle reacted with PHYH2 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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HACL1 Rabbit anti-Human Polyclonal (aa550-578) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
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HACL1 Rabbit anti-Human Polyclonal (aa550-578) Antibody
Mouse, Human
ELISA, WB
Unconjugated
200 µl/$734
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HACL1 Rabbit anti-Human Polyclonal (aa550-578) (Biotin) Antibody
Mouse, Human
ELISA, WB
Biotin Conjugated
200 µl/$952
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HACL1 Rabbit anti-Human Polyclonal (aa550-578) (FITC) Antibody
Mouse, Human
ELISA, WB
FITC Conjugated
200 µl/$952
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HACL1 Rabbit anti-Human Polyclonal (aa550-578) (APC) Antibody
Mouse, Human
ELISA, WB
APC Conjugated
200 µl/$952
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HACL1 Rabbit anti-Human Polyclonal (aa550-578) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
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HACL1 Rabbit anti-Human Polyclonal (aa550-578) (PE) Antibody
Mouse, Human
ELISA, WB
PE Conjugated
200 µl/$952
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HACL1 Mouse anti-Human Polyclonal Antibody
Human
IF, WB
Unconjugated
50 µg/$705
HACL1 Antibody - Detection of human and mouse HACL1 by western blot. Samples: Whole cell lysate (15 µg) from HeLa, HEK293T, Jurkat, mouse TCMK-1, and mouse NIH 3T3 cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-HACL1 antibody used for WB at 1:1000. Detection: Chemiluminescence with an exposure time of 3 minutes.
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HACL1 Rabbit anti-Human Polyclonal (aa528-578) Antibody
Mouse, Human
IP, WB
Unconjugated
10 µl/$295
HACL1 Antibody -  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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HACL1 Rabbit anti-Human Polyclonal (aa102-151) Antibody
Human
WB
Unconjugated
100 µl/$424
HACL1 Antibody -  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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HACL1 Rabbit anti-Human Polyclonal (aa102-151) (HRP) Antibody
Guinea pig, Human, Chimpanzee, Orangutan, Gibbon
WB
HRP Conjugated
100 µl/$469
HACL1 Antibody -  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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HACL1 Rabbit anti-Human Polyclonal (aa102-151) (Biotin) Antibody
Guinea pig, Human, Chimpanzee, Orangutan, Gibbon
WB
Biotin Conjugated
100 µl/$469
HACL1 Antibody -  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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HACL1 Rabbit anti-Human Polyclonal (aa102-151) (FITC) Antibody
Guinea pig, Human, Chimpanzee, Orangutan, Gibbon
WB
FITC Conjugated
100 µl/$469
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293T Cells
Myc-DDK (Flag)
63.5 kDa
20 µg/$150
HACL1 Protein - 12.5% SDS-PAGE of human HACL1 stained with Coomassie Blue
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Wheat Germ Extract
GST
90.1 kDa
10 µg/$479; 25 µg/$670
HACL1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
63.5 kDa
100 µg/$494
HACL1 Protein - Purified recombinant protein HACL1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
63.5 kDa
20 µg/$1,107
Viewing 1-19 of 19 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).