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Cleaves the alpha-chain at multiple sites and the beta-chain between 'Lys-53' and 'Lys-54' but not the gamma-chain of fibrinogen and therefore does not initiate the formation of the fibrin clot and does not cause the fibrinolysis directly. It does not cleave (activate) prothrombin and plasminogen but converts the inactive single chain urinary plasminogen activator (pro-urokinase) to the active two chain form. Activates coagulation factor VII.
Gene Name: | hyaluronan binding protein 2 |
Family/Subfamily: | Protease , Serine S1 |
Synonyms: | HABP2, Factor VII activating protein, Factor VII, FSAP, HABP, Hyaluronan binding protein 2, Factor VII-activating protease, HGFAL, Hyaluronan-binding protein 2, PHBP |
Target Sequences: | NM_004132 NP_004123.1 Q14520 |
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