Granzyme A antibody LS-C526370 is a biotin-conjugated mouse monoclonal antibody to human Granzyme A (GZMA). Validated for IHC and WB.
(tested or 100% immunogen sequence identity)
Recognizes Granzyme A, a 60kD disulfide-linked homodimeric protein expressed in cytoplasmic granules of cytotoxic lymphocytes. The biological function of Granzyme A is unclear. It would appear that the molecule may have a role in the induction of apoptosis via its activity as a serine protease, but this would seem to be subsidiary to the role of Granzyme B. Granzyme A deficient mice are indistinguishable from normal animals in their response to infection.