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GSAP / PION

gamma-secretase activating protein

Regulator of gamma-secretase activity, which specifically activates the production of beta-amyloid protein (beta-amyloid protein 40 and beta-amyloid protein 42), without affecting the cleavage of other gamma-secretase targets such has Notch. The gamma-secretase complex is an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Specifically promotes the gamma-cleavage of APP CTF-alpha (also named APP-CTF) by the gamma-secretase complex to generate beta-amyloid, while it reduces the epsilon-cleavage of APP CTF-alpha, leading to a low production of AICD.

Gene Name: gamma-secretase activating protein
Synonyms: GSAP, Protein pigeon homolog, LOC54103, Pigeon homolog (Drosophila), PION
Target Sequences: NP_059135.2 A4D1B5

☰ Filters
Antibodies (29)
ELISA Kits (4)
Proteins (1)
Custom (2)
Primary (29)
Recombinant (1)
Sandwich (2)
GSAP / PION (34)
Human (31)
Mouse (2)
Rat (2)
IHC (8)
IHC-P (1)
WB (29)
ELISA (7)
IF (1)
rabbit (29)
IgG (7)
polyclonal pc (29)
96-Well Strip Plate (4)
APC (1)
APC Conjugated (2)
Biotin Conjugated (5)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
DY488 Conjugated (2)
DY550 Conjugated (2)
DY650 Conjugated (2)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (2)
Unconjugated (6)
aa616-854 (8)
aa537-565 (7)
N-Terminus (4)
No (34)
Plasma (1)
Serum (1)
Tissue Homogenates (2)
His-T7 (1)
Human (1)
E. coli (1)
GSAP / PION Antibody - Immunohistochemistry of PION in human brain tissue with PION antibody at 5 ug/ml.
Select
GSAP / PION Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
0.1 mg/$460
Select
GSAP / PION Rabbit anti-Human Polyclonal (aa537-565) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
Select
GSAP / PION Rabbit anti-Human Polyclonal (aa537-565) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated
200 µl/$952
Select
GSAP / PION Rabbit anti-Human Polyclonal (aa537-565) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
Select
GSAP / PION Rabbit anti-Human Polyclonal (aa537-565) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
Select
GSAP / PION Rabbit anti-Human Polyclonal (aa537-565) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
Select
GSAP / PION Rabbit anti-Human Polyclonal (aa537-565) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
GSAP / PION Antibody - PION Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human skeletal muscle followed by peroxidase-conjugated secondary antibody and DAB staining.
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GSAP / PION Rabbit anti-Human Polyclonal (aa537-565) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
GSAP / PION Antibody - Western blot of GSAP Antibody with human 721_B Whole Cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GSAP / PION Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
GSAP / PION Antibody - Western blot of GSAP Antibody with human 721_B Whole Cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
GSAP / PION Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$469
GSAP / PION Antibody - Western blot of GSAP Antibody with human 721_B Whole Cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
GSAP / PION Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$469
GSAP / PION Antibody - Western blot of GSAP Antibody with human 721_B Whole Cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
GSAP / PION Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$469
GSAP / PION Antibody - Western Blot: GSAP Antibody - Analysis of GSAP in HepG2 cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
GSAP / PION Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
0.1 ml/$386
GSAP / PION Antibody - Western Blot: GSAP Antibody - Analysis of GSAP in HepG2 cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
GSAP / PION Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
WB
Biotin Conjugated
0.1 ml/$416
GSAP / PION Antibody - Western Blot: GSAP Antibody - Analysis of GSAP in HepG2 cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
GSAP / PION Rabbit anti-Human Polyclonal (DY650) Antibody
Human
WB
DY650 Conjugated
0.1 ml/$416
GSAP / PION Antibody - Western Blot: GSAP Antibody - Analysis of GSAP in HepG2 cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
GSAP / PION Rabbit anti-Human Polyclonal (DY488) Antibody
Human
WB
DY488 Conjugated
0.1 ml/$416
GSAP / PION Antibody - Western Blot: GSAP Antibody - Analysis of GSAP in HepG2 cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
GSAP / PION Rabbit anti-Human Polyclonal (DY550) Antibody
Human
WB
DY550 Conjugated
0.1 ml/$416
GSAP / PION Antibody - Western blot of recombinant GSAP / PION.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
GSAP / PION Rabbit anti-Human Polyclonal (aa616-854) Antibody
Human
WB
Unconjugated
100 µl/$318; 200 µl/$364; 500 µl/$518; 1 ml/$595; 2 ml/$822; 5 ml/$1,345
GSAP / PION Antibody - Western blot of recombinant GSAP / PION.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
GSAP / PION Rabbit anti-Human Polyclonal (aa616-854) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$329; 200 µl/$379; 500 µl/$549; 1 ml/$651; 2 ml/$886; 5 ml/$1,479
GSAP / PION Antibody - Western blot of recombinant GSAP / PION.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
GSAP / PION Rabbit anti-Human Polyclonal (aa616-854) (APC, Cy7) Antibody
Human
WB
APC, Cy7 Conjugated
100 µl/$533; 200 µl/$709; 500 µl/$1,229; 1 ml/$1,537; 2 ml/$2,151; 5 ml/$4,033
GSAP / PION Antibody - Western blot of recombinant GSAP / PION.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
GSAP / PION Rabbit anti-Human Polyclonal (aa616-854) (PE) Antibody
Human
WB
PE Conjugated
100 µl/$426; 200 µl/$518; 500 µl/$913; 1 ml/$1,080; 2 ml/$1,435; 5 ml/$2,689
Select
GSAP / PION Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
WB
Biotin Conjugated
0.1 ml/$416
Select
GSAP / PION Rabbit anti-Human Polyclonal (DY488) Antibody
Human
WB
DY488 Conjugated
0.1 ml/$416
Select
GSAP / PION Rabbit anti-Human Polyclonal (DY650) Antibody
Human
WB
DY650 Conjugated
0.1 ml/$416
Select
GSAP / PION Rabbit anti-Human Polyclonal (DY550) Antibody
Human
WB
DY550 Conjugated
0.1 ml/$416
Viewing 1-25 of 34 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).