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GRM8 / MGLUR8

glutamate receptor, metabotropic 8

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Gene Name: glutamate receptor, metabotropic 8
Family/Subfamily: GPCR , Metabotropic glutamate
Synonyms: GRM8, GLUR8, GPRC1H, MGlu8, MGLUR8
Target Sequences: NM_000845 NP_000836.2 O00222

☰ Filters
Antibodies (22)
Proteins (5)
ELISA Kits (1)
Cell-Based (1)
Over-Expression Lysate (4)
Primary (22)
Recombinant (1)
GRM8 / MGLUR8 (28)
Human (23)
Mouse (17)
Rat (11)
Bat (3)
Chicken (1)
Dog (1)
Hamster (1)
Horse (3)
Monkey (3)
Rabbit (2)
Sheep (1)
IHC (10)
IHC-P (4)
WB (18)
Flo (1)
ELISA (11)
ICC (1)
Peptide-ELISA (2)
rabbit (20)
mouse (2)
Product Group
GPCR Database Antibodies (3)
IHCPlus (2)
PathPlus Neuro (2)
IgG (12)
IgG1 (1)
IgG2a,k (1)
monoclonal mc (2)
polyclonal pc (20)
4A7 (1)
4C1C1 (1)
96-Well Microplate (1)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
PE Conjugated (1)
Unconjugated (17)
aa852-882 (7)
C-Terminus (2)
N-Terminus (2)
810-890 aa, C-terminal (1)
aa841-890 (1)
No (28)
Adherent Cell Cultures (1)
GST, N-terminus (1)
Myc-DDK (Flag) (4)
Human (3)
293T Cells (2)
HEK 293 Cells (2)
Wheat Germ Extract (1)
GRM8 / MGLUR8 Antibody - Anti-GRM8 / MGLUR8 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 6 ug/ml.
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GRM8 / MGLUR8 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Chicken, Sheep, Rat, Hamster, Horse, Bat, Rabbit, Mouse, Dog, Human, Monkey
ICC, IHC, IHC-P
Unconjugated
50 µg/$440
GRM8 / MGLUR8 Antibody - Anti-GRM8 / MGLUR8 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Neuroscience
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GRM8 / MGLUR8 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Rat, Horse, Bat, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$440
GRM8 / MGLUR8 Antibody - Anti-GRM8 / MGLUR8 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Neuroscience
Fast Shipping
GRM8 / MGLUR8 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Rabbit, Horse, Bat, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$460
GRM8 / MGLUR8 Antibody - The GRPRC1H C-term antibody is used in Western blot to detect GRPRC1H in mouse brain tissue lysate.
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GRM8 / MGLUR8 Rabbit anti-Human Polyclonal (aa852-882) Antibody
Mouse, Human
WB
Unconjugated
400 µl/$393
GRM8 / MGLUR8 Antibody - Anti-GRM8 / MGLUR8 antibody IHC of human brain, cortex neurons. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
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GRM8 / MGLUR8 Rabbit anti-Human Polyclonal (aa841-890) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
GRM8 / MGLUR8 Antibody - Western blot of mouse brain cell lysate using mGluR8 Antibody
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GRM8 / MGLUR8 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µg/$305; 100 µg/$357
GRM8 / MGLUR8 Antibody - Detection limit for recombinant GST tagged GRM8 is 0.3 ng/ml as a capture antibody.
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GRM8 / MGLUR8 Mouse anti-Human Monoclonal (4A7) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
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GRM8 / MGLUR8 Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
100 µg/$386
GRM8 / MGLUR8 Antibody - Western blot analysis of mGLUR8 expression in EOC20 (A); rat brain (B) whole cell lysates.
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GRM8 / MGLUR8 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Rat, Human
WB
Unconjugated
100 µl/$299
GRM8 / MGLUR8 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
101.61 kDa
20 µg/$215
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GRM8 / MGLUR8 Mouse anti-Human Monoclonal (4C1C1) Antibody
Human
ELISA, Flo, WB
Unconjugated
100 µl/$459
GRM8 / MGLUR8 Antibody - Immunohistochemistry of paraffin-embedded human ovarian cancer tissue.
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GRM8 / MGLUR8 Rabbit anti-Human Polyclonal Antibody
Human
IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
GRM8 / MGLUR8 Antibody - Immunohistochemistry of mGluR-8 antibody
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GRM8 / MGLUR8 Rabbit anti-Human Polyclonal (810-890 aa, C-terminal) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
GRM8 / MGLUR8 Antibody - Peptide - + Immunohistochemical analysis of paraffin-embedded human brain tissue using GluR8 antibody.
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GRM8 / MGLUR8 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100 µg/$357
GRM8 / MGLUR8 Antibody - 1:100 staining human colorectal carcinoma tissue by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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GRM8 / MGLUR8 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
GRM8 / MGLUR8 Antibody - Western blot of GluR8 expression in Mouse brain extract
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GRM8 / MGLUR8 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µg/$305; 100 µg/$357
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GRM8 / MGLUR8 Rabbit anti-Human Polyclonal (aa852-882) Antibody
Mouse, Human
ELISA, WB
Unconjugated
200 µl/$734
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GRM8 / MGLUR8 Rabbit anti-Human Polyclonal (aa852-882) (Biotin) Antibody
Mouse, Human
ELISA, WB
Biotin Conjugated
200 µl/$952
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GRM8 / MGLUR8 Rabbit anti-Human Polyclonal (aa852-882) (FITC) Antibody
Mouse, Human
ELISA, WB
FITC Conjugated
200 µl/$952
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GRM8 / MGLUR8 Rabbit anti-Human Polyclonal (aa852-882) (APC) Antibody
Mouse, Human
ELISA, WB
APC Conjugated
200 µl/$952
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GRM8 / MGLUR8 Rabbit anti-Human Polyclonal (aa852-882) (PE) Antibody
Mouse, Human
ELISA, WB
PE Conjugated
200 µl/$952
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GRM8 / MGLUR8 Rabbit anti-Human Polyclonal (aa852-882) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
GRM8 / MGLUR8 Antibody - Western blot analysis of extracts of various cell lines using GRM8 Polyclonal Antibody at dilution of 1:1000.
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GRM8 / MGLUR8 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
GRM8 / MGLUR8 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
GRM8 / MGLUR8 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
101.74 kDa
20 µg/$150
Viewing 1-25 of 28 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).