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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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GRK4 Antibody (aa359‑408, FITC) LS‑C457752
GRK4 antibody LS-C457752 is an FITC-conjugated rabbit polyclonal antibody to GRK4 from human, mouse, rat and other species. Validated for WB.
Catalog
Size
Price
LS-C457752-100
100 µl (1 mg/ml)
$385

Popular GRK4 Products

Immunohistochemistry of paraffin-embedded human liver cancer using antibody at 1: 100 dilution.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, ELISA
Immunohistochemistry of paraffin-embedded human liver cancer using antibody at 1: 100 dilution.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, ELISA
Immunohistochemistry of paraffin-embedded human liver cancer using antibody at 1: 100 dilution.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, ELISA
Immunohistochemistry of paraffin-embedded human liver cancer using antibody at 1: 100 dilution.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, ELISA
Immunohistochemistry of Human ovarian cancer using GRK4 Polyclonal Antibody at dilution of 1:40.
Species: Human
Applications: IHC, Western blot, ELISA

Product Description

GRK4 antibody LS-C457752 is an FITC-conjugated rabbit polyclonal antibody to GRK4 from human, mouse, rat and other species. Validated for WB.

Specifications

Target
Human GRK4
Synonyms
GRK4, GPRK4, GPRK2L, GRK4a, IT11, ITI1
Host
Rabbit
Reactivity
Human, Chimpanzee, Gibbon, Monkey, Mouse, Rat, Bovine, Horse (tested or 100% immunogen sequence identity)
Predicted
Dog, Guinea pig, Xenopus, Zebrafish (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Fluorescein. Also available Unconjugated or conjugated with Biotin, HRP.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot
  • (applications tested for the base form of this product only)
Immunogen
GRK4 antibody was raised against synthetic peptide located between aa359-408 of human GRK4 (P32298, NP_001004056). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Galago, Marmoset, Horse (100%); Elephant, Guinea pig, Xenopus (92%); Dog (91%); Stickleback, Zebrafish (90%); Mouse (85%); Bat, Platypus (84%); Rat (76%).
Epitope
aa359-408
Specificity
Human GRK4
Usage
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
PBS
Storage
Short term: store at 4°C. Long term: add glycerol to 40-50%, aliquot to avoid freeze-thaw cycles, and store at -20°C. Protect from light.
Restrictions
For research use only.
About GRK4
Specifically phosphorylates the activated forms of G protein-coupled receptors. GRK4-alpha can phosphorylate rhodopsin and its activity is inhibited by calmodulin; the other three isoforms do not phosphorylate rhodopsin and do not interact with calmodulin. GRK4-alpha and GRK4-gamma phosphorylate DRD3. Phosphorylates ADRB2. P32298 NM_182982 NP_892027.2


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Images

Western blot

GRK4 antibody Western blot of MCF7 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
GRK4 antibody Western blot of MCF7 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

GRK4 antibody Western blot of MCF7 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
GRK4 antibody Western blot of MCF7 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

GRK4 antibody Western blot of MCF7 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
GRK4 antibody Western blot of MCF7 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

GRK4 antibody Western blot of MCF7 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
GRK4 antibody Western blot of MCF7 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Requested From: United States
Date Requested: 11/14/2018

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