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GPR80 / GPR99 / OXGR1

oxoglutarate (alpha-ketoglutarate) receptor 1

Receptor for alpha-ketoglutarate. Seems to act exclusively through a G(q)-mediated pathway.

Gene Name: oxoglutarate (alpha-ketoglutarate) receptor 1
Family/Subfamily: GPCR , Purinergic
Synonyms: OXGR1, 2-oxoglutarate receptor 1, Alpha-ketoglutarate receptor 1, G protein-coupled receptor 80, GPR80, G-protein coupled receptor 99, GPR99, p2Y purinoceptor 15, p2Y-like nucleotide receptor, p2RY15, Oxoglutarate receptor 1, p2Y-like GPCR, p2Y15, G protein-coupled receptor 99, G-protein coupled receptor 80
Target Sequences: NM_080818 NP_543008.3 Q96P68

Publications (2)

1
Exercise-induced a-ketoglutaric acid stimulates muscle hypertrophy and fat loss through OXGR1-dependent adrenal activation. Yexian Yuan , Pingwen Xu , Qingyan Jiang , Xingcai Cai, Tao Wang, Wentong Peng, Jiajie Sun, Canjun Zhu, Cha Zhang, Dong Yue, Zhihui He, Jinping Yang, Yuxian Zeng, Man Du, Fenglin Zhang, Lucas Ibrahimi, Sarah Schaul, Yuwei Jiang, Jiqiu Wang, Jia Sun, Qiaoping Wang, Liming Liu, Songbo Wang, Lina Wang, Xiaotong Zhu, Ping Gao, Qianyun Xi, Cong Yin, Fan Li, Guli Xu, Yongliang Zhang, Gang Shu. The EMBO journal. 2020 Apr;39:e103304. [Full Text Article] [PubMed:32104923] [PMC:PMC7110140] Related Antibodies: LS-A1865.
2
alpha -Ketoglutarate regulates acid-base balance through an intrarenal paracrine mechanism. Tokonami N, Morla L, Centeno G, Mordasini D, Ramakrishnan SK, Nikolaeva S, Wagner CA, Bonny O, Houillier P, Doucet A, Firsov D. The Journal of clinical investigation. 2013 Jul;123:3166-71. [Full Text Article] [PubMed:23934124] [PMC:PMC3696567] Related Antibodies: LS-A1865.

☰ Filters
Antibodies (7)
Proteins (3)
Over-Expression Lysate (2)
Primary (7)
Recombinant (1)
GPR80 / GPR99 / OXGR1 (10)
Human (7)
Mouse (3)
Rat (3)
Monkey (1)
IHC (3)
IHC-P (3)
WB (4)
ELISA (2)
Peptide-ELISA (1)
rabbit (7)
Product Group
GPCR Database Antibodies (3)
IHCPlus (1)
PathPlus Neuro (2)
IgG (2)
polyclonal pc (7)
Unconjugated (7)
Extracellular Domain (2)
N-Terminus (1)
aa309-337 (1)
No (9)
Yes (1)
GST (1)
Myc-DDK (Flag) (2)
Human (2)
293T Cells (1)
HEK 293 Cells (1)
Wheat Germ Extract (1)
Purified (1)
GPR80 / GPR99 / OXGR1 Antibody - Anti-OXGR1 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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GPR80 / GPR99 / OXGR1 Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$440
GPR80 / GPR99 / OXGR1 Antibody - Anti-OXGR1 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Neuroscience
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GPR80 / GPR99 / OXGR1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$440
GPR80 / GPR99 / OXGR1 Antibody - Anti-GPR80 / GPR99 / OXGR1 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Neuroscience
Fast Shipping
GPR80 / GPR99 / OXGR1 Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$440
GPR80 / GPR99 / OXGR1 Antibody - OXGR1 Antibody western blot of human placenta tissue lysates (35 ug/lane). The OXGR1 antibody detected the OXGR1 protein (arrow).
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GPR80 / GPR99 / OXGR1 Rabbit anti-Human Polyclonal (aa309-337) Antibody
Human
WB
Unconjugated
400 µl/$393
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GPR80 / GPR99 / OXGR1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
GPR80 / GPR99 / OXGR1 Antibody - Western blot analysis of GPR80/GPR99 expression in human placenta tissue lysates. The lane on the left is treated with the antigen-specific peptide.
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GPR80 / GPR99 / OXGR1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
GPR80 / GPR99 / OXGR1 Antibody - Western blot analysis of extracts of various cell lines, using OXGR1 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 10s.
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GPR80 / GPR99 / OXGR1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
GPR80 / GPR99 / OXGR1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
38.1 kDa
20 µg/$150
GPR80 / GPR99 / OXGR1 Protein - 12.5% SDS-PAGE of human OXGR1 stained with Coomassie Blue
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Wheat Germ Extract
GST
64.7 kDa
2 µg/$439
GPR80 / GPR99 / OXGR1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
38.1 kDa
100 µg/$494
Viewing 1-10 of 10 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).