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GPR50

G protein-coupled receptor 50

GPR50 belongs to the G-protein coupled receptor 1 family. Even though this protein shares similarity with the melatonin receptors, it does not bind melatonin, however, it inhibits melatonin receptor 1A function through heterodimerization. Polymorphic variants of this gene have been associated with bipolar affective disorder in women.

Gene Name: G protein-coupled receptor 50
Family/Subfamily: GPCR , Orphan-A
Synonyms: GPR50, G protein-coupled receptor 50, Mel1c, Melatonin-related receptor, MTNRL, H9
Target Sequences: NM_004224 NP_004215.2 Q13585

Publications (1)

1
The orphan GPR50 receptor specifically inhibits MT1 melatonin receptor function through heterodimerization. Levoye A, Dam J, Ayoub MA, Guillaume JL, Couturier C, Delagrange P, Jockers R. The EMBO journal. 2006 25:3012-23. (WB; Human) [Full Text Article] [PubMed:16778767] [PMC:PMC1500982] Related Antibodies: LS-A6621.

☰ Filters
Antibodies (31)
Proteins (3)
Over-Expression Lysate (2)
Primary (31)
Recombinant (1)
GPR50 (34)
Human (31)
Mouse (2)
Rat (2)
Chimpanzee (3)
Dog (2)
Monkey (3)
Sheep (2)
IHC (6)
IHC-Fr (1)
IHC-P (5)
WB (25)
Flo (9)
ELISA (10)
IF (6)
Peptide-ELISA (2)
rabbit (29)
mouse (2)
Product Group
GPCR Database Antibodies (4)
IHCPlus (2)
PathPlus Neuro (2)
IgG (19)
IgG1,k (1)
monoclonal mc (1)
polyclonal pc (30)
1A3 (1)
APC Conjugated (2)
Azide-free (1)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (2)
Unconjugated (18)
aa316-344 (7)
aa323-372 (4)
C-Terminus (2)
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270-350 aa, Internal (1)
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aa301-350 (1)
aa345-390 (1)
No (33)
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Purified (1)
GPR50 Antibody - Anti-GPR50 antibody IHC of human pituitary. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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GPR50 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µg/$460
GPR50 Antibody - Anti-GPR50 antibody IHC of human brain, hypothalamus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Neuroscience
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GPR50 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Dog, Sheep, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$440
GPR50 Antibody - Anti-GPR50 antibody IHC of human pituitary. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Fast Shipping
GPR50 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Dog, Sheep, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$440
GPR50 Antibody - Anti-GPR50 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Neuroscience
Fast Shipping
GPR50 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$440
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GPR50 Rabbit anti-Human Polyclonal (aa345-390) Antibody
Mouse, Rat, Human
IF, WB
Unconjugated
50 µl/$321; 100 µl/$403
GPR50 Antibody - Immunofluorescence analysis of LOVO cells, using MTR1L Antibody. The picture on the right is blocked with the synthesized peptide.
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GPR50 Rabbit anti-Human Polyclonal (aa301-350) Antibody
Human
IF, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
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GPR50 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, Flo, IF, IHC, WB
Unconjugated
100 µg/$341
GPR50 Antibody - Western blot analysis of GPR50 expression in HeLa (A); SP2/0 (B); PC12 (C) whole cell lysates.
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GPR50 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µl/$299
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GPR50 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, Flo, IF, WB
Unconjugated
100 µg/$341
GPR50 Antibody - Clone 1A3 human pituitary, paraffin section
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GPR50 Mouse anti-Human Monoclonal (1A3) Antibody
Human
IHC, IHC-Fr, IHC-P
Unconjugated
250 µg/$575
GPR50 Antibody - Western blot of GPR50 antibody
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GPR50 Rabbit anti-Human Polyclonal (270-350 aa, Internal) Antibody
Human
ELISA, IF, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
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GPR50 Rabbit anti-Human Polyclonal (aa316-344) Antibody
Human
ELISA, Flo, WB
Unconjugated
200 µl/$734
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GPR50 Rabbit anti-Human Polyclonal (aa316-344) (Biotin) Antibody
Human
ELISA, Flo, WB
Biotin Conjugated
200 µl/$952
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GPR50 Rabbit anti-Human Polyclonal (aa316-344) (FITC) Antibody
Human
ELISA, Flo, WB
FITC Conjugated
200 µl/$952
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GPR50 Rabbit anti-Human Polyclonal (aa316-344) (Azide-free) (HRP) Antibody
Human
ELISA, Flo, WB
HRP Conjugated, Azide-free
200 µl/$952
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GPR50 Rabbit anti-Human Polyclonal (aa316-344) (APC) Antibody
Human
ELISA, Flo, WB
APC Conjugated
200 µl/$952
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GPR50 Rabbit anti-Human Polyclonal (aa316-344) (PE) Antibody
Human
ELISA, Flo, WB
PE Conjugated
200 µl/$952
GPR50 Antibody - Peptide - + Immunofluorescence analysis of LOVO cells, using MTR1L antibody.
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GPR50 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF
Unconjugated
100 µg/$357
GPR50 Antibody - Western blot of GPR50 Antibody in K562 cell line lysates (35 ug/lane). GPR50 (arrow) was detected using the purified antibody.
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GPR50 Rabbit anti-Human Polyclonal (aa316-344) Antibody
Human
Flo, WB
Unconjugated
400 µl/$393
GPR50 Antibody - Western blot analysis GPR50 using K562 whole cells lysates
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GPR50 Rabbit anti-Human Polyclonal Antibody
Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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GPR50 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µg/$749
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GPR50 Rabbit anti-Human Polyclonal (PE) Antibody
Human
WB
PE Conjugated
100 µl/$937
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GPR50 Rabbit anti-Human Polyclonal (APC) Antibody
Human
WB
APC Conjugated
100 µl/$937
GPR50 Antibody - GPR50 antibody Western Blot of Jurkat.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GPR50 Rabbit anti-Human Polyclonal (aa323-372) Antibody
Human
WB
Unconjugated
100 µl/$424
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GPR50 Mouse anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µg/$705
Viewing 1-25 of 34 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).