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GPR182 / ADMR

G protein-coupled receptor 182

G Protein-Coupled Receptor L1/G10D (GPR182) has been suggested to be an Adrenomedullin Receptor. Originally cloned from rats and later from humans, L1/G10D does not to bind adrenomedullin or display functional cAMP response to adrenomedullin (reviewed in Poyner et al. 2002). The initial experimental results, which demonstrated high-affinity binding and increased levels of cAMP in COS cells that were transfected with L1/G10D and treated with adrenomedullin, could not be reproduced by other laboratories (Kapas et al. 1995). It is now known that the functional adrenomedullin receptor is a heterodimeric complex composed of calcitonin receptor-like receptor (CRLR) and receptor activity modifying proteins (RAMPs) ( McLatchie et al. 1998). L1/G10D therefore should be considered an Orphan A receptor.

Gene Name: G protein-coupled receptor 182
Family/Subfamily: GPCR , Orphan-A
Synonyms: GPR182, 7TMR, Adrenomedullin L1 receptor, AM-R, AMR, ADMR, Adrenomedullin receptor, G protein-coupled receptor 182, HrhAMR, G-protein coupled receptor 182, Gamrh, HAMR, RAMR, G10D
Target Sequences: NM_007264 NP_009195.1 O15218

Publications (1)

1
The ADMR receptor mediates the effects of adrenomedullin on pancreatic cancer cells and on cells of the tumor microenvironment. Ramachandran V, Arumugam T, Langley R, Hwang RF, Vivas-Mejia P, Sood AK, Lopez-Berestein G, Logsdon CD. PloS one. 2009 4:e7502. (WB; Human) [Full Text Article] [PubMed:19847298] [PMC:PMC2760778] Related Antibodies: LS-A4048.

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Antibodies (20)
Proteins (3)
ELISA Kits (1)
Over-Expression Lysate (2)
Primary (20)
Recombinant (1)
Sandwich (1)
GPR182 / ADMR (24)
Human (21)
Mouse (4)
Rat (2)
Monkey (3)
IHC (8)
IHC-P (7)
WB (14)
ELISA (13)
ICC (2)
IF (1)
Peptide-ELISA (1)
rabbit (14)
mouse (6)
Product Group
GPCR Database Antibodies (7)
IHCPlus (5)
PathPlus Neuro (2)
IgG (3)
IgG2a,k (6)
monoclonal mc (6)
polyclonal pc (14)
96-Well Strip Plate (1)
APC Conjugated (1)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
PE Conjugated (1)
Unconjugated (15)
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aa1-55 (1)
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Tissue Homogenates (1)
GST, N-terminus (1)
Myc-DDK (Flag) (2)
Human (2)
293T Cells (1)
HEK 293 Cells (1)
Wheat Germ Extract (1)
GPR182 / ADMR Antibody - Anti-GPR182 / ADMR antibody IHC of human Lung, Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Neuroscience
GPR182 / ADMR Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human, Monkey
ICC, IHC, IHC-P, WB
Unconjugated
50 µg/$460
GPR182 / ADMR Antibody - Anti-GPR182 / ADMR antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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GPR182 / ADMR Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$460
GPR182 / ADMR Antibody - Anti-GPR182 / ADMR antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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GPR182 / ADMR Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$460
GPR182 / ADMR Antibody - Brain, Caudate neuron
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Neuroscience
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GPR182 / ADMR Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Human
ICC, IHC, IHC-P
Unconjugated
50 µg/$460
GPR182 / ADMR Antibody - Anti-GPR182 / ADMR antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Fast Shipping
GPR182 / ADMR Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human, Monkey
ELISA, IHC, IHC-P
Unconjugated
50 µg/$460
GPR182 / ADMR Antibody - Anti-GPR182 / ADMR antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Fast Shipping
GPR182 / ADMR Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$460
GPR182 / ADMR Antibody - Anti-GPR182 / ADMR antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Fast Shipping
GPR182 / ADMR Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Human, Monkey
ELISA, IHC, IHC-P
Unconjugated
50 µg/$460
GPR182 / ADMR Antibody - Immunohistochemistry of paraffin-embedded Human thyroid cancer using GPR182 Polyclonal Antibody at dilution of 1:25.
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GPR182 / ADMR Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
GPR182 / ADMR Antibody - Western blot analysis GPR182 using HT29 whole cells lysates
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GPR182 / ADMR Rabbit anti-Human Polyclonal Antibody
Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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GPR182 / ADMR Mouse anti-Human Monoclonal (aa1-55) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$705
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GPR182 / ADMR Mouse anti-Human Monoclonal (HRP) Antibody
Human
ELISA, WB
HRP Conjugated
100 µl/$904
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GPR182 / ADMR Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
100 µl/$904
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GPR182 / ADMR Mouse anti-Human Monoclonal (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
100 µl/$904
Select
GPR182 / ADMR Mouse anti-Human Monoclonal (PE) Antibody
Human
ELISA, WB
PE Conjugated
100 µl/$904
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GPR182 / ADMR Mouse anti-Human Monoclonal (APC) Antibody
Human
ELISA, WB
APC Conjugated
100 µl/$904
Select
GPR182 / ADMR Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
ELISA, WB
Unconjugated
0.1 mg/$379
Select
GPR182 / ADMR Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$357
Select
GPR182 / ADMR Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
50 µl/$321; 100 µl/$403
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GPR182 / ADMR Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
GPR182 / ADMR Antibody - Western blot analysis of GPR182 expression in A549 (A); Raw264.7 (B); PC12 (C) whole cell lysates.
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GPR182 / ADMR Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µl/$299
GPR182 / ADMR Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
GPR182 / ADMR Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
45.1 kDa
20 µg/$150
GPR182 / ADMR ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$834
GPR182 / ADMR Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
45.1 kDa
100 µg/$494
Viewing 1-24 of 24 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).