GPNMB / Osteoactivin

glycoprotein (transmembrane) nmb

GPNMB / Osteoactivin is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.

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Products

Antibodies (56)

Proteins (16)

ELISA Kits (12)

Type

Custom (3)

Over-Expression Lysate (2)

Primary (56)

Recombinant (14)

Sandwich (9)

Target

GPNMB / Osteoactivin (84)

Reactivity

Human (58)

Mouse (20)

Rat (10)

Bat (3)

Bovine (6)

Chimpanzee (6)

Dog (9)

Gibbon (9)

Guinea pig (3)

Hamster (6)

Horse (6)

Monkey (3)

Pig (3)

Rabbit (6)

Zebrafish (3)

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Application

IHC (17)

IHC-P (10)

WB (46)

ELISA (22)

ICC (1)

IF (2)

Peptide-ELISA (1)

SDS-PAGE (3)

Host

rabbit (30)

mouse (26)

Product Group

IHCPlus (2)

Isotype

IgG (23)

IgG1 (15)

IgG1,k (6)

IgG2a (4)

IgG2a,k (1)

Clonality

monoclonal mc (26)

polyclonal pc (30)

Clone

1A8 (1)

3A5 (1)

7C10E5 (1)

OTI1E3 (2)

OTI1G10 (2)

OTI2A10 (2)

OTI2E10 (2)

OTI2F9 (2)

OTI2H7 (2)

OTI5C2 (2)

OTI7E3 (2)

OTI8A10 (2)

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Format

96-Well Microplate (4)

96-Well Strip Plate (8)

APC Conjugated (2)

Azide-free (1)

Biotin Conjugated (5)

Carrier-free (9)

FITC Conjugated (5)

HRP Conjugated (5)

PE Conjugated (2)

Preservative Free (1)

Unconjugated (37)

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Epitope

aa541-569 (7)

aa50-99 (4)

aa74-123 (4)

aa143-192 (3)

aa1-502 (2)

aa508-572 (2)

aa104-203 (1)

aa31-260 (1)

aa551-568 (1)

Publications

No (83)

Yes (1)

Sample Type

Cell Culture Supernatants (6)

Cell Supernatant (1)

Plasma (9)

Serum (9)

Tissue Homogenates (1)

Tag

6His, C-terminus (2)

Fc, C-terminus (1)

GST (1)

GST, N-terminus (1)

His (5)

His,C-terminus (2)

Human IgG Fc, C-terminus (1)

Myc-DDK (Flag) (3)

Species

Human (12)

Mouse (3)

Source

293T Cells (1)

E. coli (3)

HEK 293 Cells (6)

Human Cells (3)

Mammalian Cells (1)

Wheat Germ Extract (2)

Purification

Purified (4)

Low Endotoxin Level

Low endotoxin level (10)

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GPNMB / Osteoactivin Antibody (aa50-99) LS-B11132

(4.0) Rating

(1) Publication(s)

Antibody:

GPNMB / Osteoactivin Rabbit anti-Human Polyclonal (aa50-99) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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GPNMB / Osteoactivin Antibody (aa50-99, FITC) LS-C446241

Antibody:

GPNMB / Osteoactivin Rabbit anti-Human Polyclonal (aa50-99) (FITC) Antibody

Reactivity:

Rabbit, Mouse, Dog, Bovine, Hamster, Horse, Gibbon, Chimpanzee, Human

Applications:

IHC, IHC-P, WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• FITC

• Unconjugated
• FITC

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IHC-plus™ GPNMB / Osteoactivin Antibody (clone 3A5) LS-B6406

(4.0) Rating

Antibody:

GPNMB / Osteoactivin Mouse anti-Human Monoclonal (3A5) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

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GPNMB / Osteoactivin Antibody (aa31-260, clone 7C10E5) LS-C191872

Antibody:

GPNMB / Osteoactivin Mouse anti-Human Monoclonal (aa31-260) (7C10E5) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$459

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GPNMB / Osteoactivin Antibody (clone OTI8A10) LS-C340379

Antibody:

GPNMB / Osteoactivin Mouse anti-Human Monoclonal (OTI8A10) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$434

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GPNMB / Osteoactivin Antibody (clone OTI8A10, Carrier-free) LS-C791370

Antibody:

GPNMB / Osteoactivin Mouse anti-Human Monoclonal (Carrier-free) (OTI8A10) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

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GPNMB / Osteoactivin Antibody (aa1-502) LS-C486777

Antibody:

GPNMB / Osteoactivin Rabbit anti-Mouse Polyclonal (aa1-502) Antibody

Reactivity:

Mouse

Applications:

ELISA

Format:

Unconjugated

Price:

100 µl/$412

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Mouse GPNMB / Osteoactivin (Sandwich ELISA) ELISA Kit - LS-F50081

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Mouse

Range:

81.92 - 20000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$588

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Mouse GPNMB / Osteoactivin (Sandwich ELISA) ELISA Kit - LS-F31491

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

156 - 10000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$717

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Human GPNMB / Osteoactivin (Sandwich ELISA) ELISA Kit - LS-F2915

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

156 - 10000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$795

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GPNMB / Osteoactivin Antibody (aa74-123) LS-C80663

Antibody:

GPNMB / Osteoactivin Rabbit anti-Human Polyclonal (aa74-123) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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GPNMB / Osteoactivin Antibody (aa1-502) LS-C486780

Antibody:

GPNMB / Osteoactivin Rabbit anti-Mouse Polyclonal (aa1-502) Antibody

Reactivity:

Mouse

Applications:

ELISA

Format:

Unconjugated

Price:

100 µl/$375; 200 µl/$473; 400 µl/$648

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Mouse GPNMB / Osteoactivin Protein (Recombinant His,C-terminus) (Met1-Asn502) - LS-G49248

Source:

HEK 293 Cells

Tag:

His,C-terminus

Application:

SDS-PAGE

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

The recombinant mouse GPNMB comprises 490 amino acids and has a predicted molecular mass of 54.9 kDa. The apparent molecular mass of the protein is approximately 96 kDa in SDS-PAGE under reducing conditions due to glycosylation.

Price:

100 µg/$441; 1 mg/$2,003

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Human GPNMB / Osteoactivin (Sandwich ELISA) ELISA Kit - LS-F173

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

49.16 - 12000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$700

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GPNMB / Osteoactivin Antibody (clone 1A8, PE) LS-C650501

Antibody:

GPNMB / Osteoactivin Mouse anti-Human Monoclonal (PE) (1A8) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

100 µl/$904

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GPNMB / Osteoactivin Antibody (clone OTI1E3) LS-C340378

Antibody:

GPNMB / Osteoactivin Mouse anti-Human Monoclonal (OTI1E3) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$434

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GPNMB / Osteoactivin Antibody LS-C749273

Antibody:

GPNMB / Osteoactivin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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Human GPNMB / Osteoactivin Protein (Recombinant 6His, C-terminus) (Ala22-Pro486) - LS-G39002

Source:

Human Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

53.09kD

Price:

10 µg/$269; 50 µg/$372; 500 µg/$1,585; 1 mg/$2,157

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Human GPNMB / Osteoactivin (Sandwich ELISA) ELISA Kit - LS-F24524

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

156 - 10000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$717

Select

Human GPNMB / Osteoactivin Protein (Recombinant His) - LS-G2501

Source:

E. coli

Tag:

His

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

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GPNMB / Osteoactivin Antibody (clone OTI2A10) LS-C794138

Antibody:

GPNMB / Osteoactivin Mouse anti-Human Monoclonal (OTI2A10) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

100 µl/$434

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GPNMB / Osteoactivin Antibody (clone OTI2A10, Carrier-free) LS-C799605

Antibody:

GPNMB / Osteoactivin Mouse anti-Human Monoclonal (Carrier-free) (OTI2A10) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

GPNMB / Osteoactivin Antibody LS-C665940

Antibody:

GPNMB / Osteoactivin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$341

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GPNMB / Osteoactivin Antibody (clone OTI2F9) LS-C794125

Antibody:

GPNMB / Osteoactivin Mouse anti-Human Monoclonal (OTI2F9) Antibody

Reactivity:

Human

Applications:

IHC

Format:

Unconjugated

Price:

100 µl/$434

Select

GPNMB / Osteoactivin Antibody LS-C816456

Antibody:

GPNMB / Osteoactivin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ICC, IF

Format:

Unconjugated

Price:

100 µl/$412

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