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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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GPBAR1 / TGR5 Antibody (Cytoplasmic Domain) IHC‑plus™ LS‑A1935
TGR5 antibody LS-A1935 is an unconjugated rabbit polyclonal antibody to human TGR5 (GPBAR1). Validated for IHC. Tested on 20 paraffin-embedded human tissues.
Catalog
Size
Price
LS-A1935-50
50 µg (0.87 mg/ml)
$425
In Stock for Immediate Shipment
Description
TGR5 antibody LS-A1935 is an unconjugated rabbit polyclonal antibody to human TGR5 (GPBAR1). Validated for IHC. Tested on 20 paraffin-embedded human tissues.
Target
Human GPBAR1 / TGR5
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Predicted
Monkey, Rabbit (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (9 µg/ml)
  • (applications tested for the base form of this product only)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
GPBAR1 / TGR5 antibody was raised against synthetic 18 amino acid peptide from 3rd cytoplasmic domain of human TGR5. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon (100%); Monkey, Marmoset, Rabbit (94%); Mouse, Rat, Bat, Bovine, Hamster, Elephant, Horse, Opossum (89%); Dog (83%).
Blocking Peptide
LS-E28444 - Liquid - 50 µg - $145.00
Immunizing peptide used to generate LS-A1935. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
Cytoplasmic Domain
Specificity
Human TGR5. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only.
About GPBAR1 / TGR5
Q8TDU6 AB083601 NP_733800.1

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Immunohistochemistry

Human Uterus, Endometrium: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Uterus, Endometrium: Formalin-Fixed, Paraffin-Embedded (FFPE)

Immunohistochemistry

Human Uterus, Endometrium: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Uterus, Endometrium: Formalin-Fixed, Paraffin-Embedded (FFPE)

Immunohistochemistry

Human Uterus, Endometrium: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Uterus, Endometrium: Formalin-Fixed, Paraffin-Embedded (FFPE)

Immunohistochemistry

Human Uterus, Endometrium: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Uterus, Endometrium: Formalin-Fixed, Paraffin-Embedded (FFPE)

Requested From: United States
Date Requested: 12/14/2018
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