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GMDS / GMD

GDP-mannose 4,6-dehydratase

GDP-mannose 4,6-dehydratase (GMD; EC 4.2.1.47) catalyzes the conversion of GDP-mannose to GDP-4-keto-6-deoxymannose, the first step in the synthesis of GDP-fucose from GDP-mannose, using NADP+ as a cofactor. The second and third steps of the pathway are catalyzed by a single enzyme, GDP-keto-6-deoxymannose 3,5-epimerase, 4-reductase, designated FX in humans (MIM 137020).

Gene Name: GDP-mannose 4,6-dehydratase
Synonyms: GMDS, GDP-D-mannose dehydratase, GDP-mannose 4,6 dehydratase, GDP-mannose 4,6-dehydratase, GMD, SDR3E1
Target Sequences: NP_001491.1 O60547

Publications (1)

1
Glycomic Profiling Highlights Increased Fucosylation in Pseudomyxoma Peritonei. Saarinen L, Nummela P, Leinonen H, Heiskanen A, Thiel A, Haglund C, Lepistö A, Satomaa T, Hautaniemi S, Ristimäki A. Molecular & cellular proteomics : MCP. 2018 November;17:2107-2118. [Full Text Article] [PubMed:30072579] [PMC:PMC6210226] Related Antibodies: LS-B12961.

☰ Filters
Antibodies (24)
Proteins (6)
Over-Expression Lysate (2)
Primary (24)
Recombinant (4)
GMDS / GMD (30)
Human (24)
Mouse (13)
Rat (4)
Bat (3)
Bovine (3)
Chicken (3)
Chimpanzee (3)
Dog (3)
Gibbon (3)
Hamster (3)
Horse (3)
Monkey (3)
Orangutan (3)
Rabbit (3)
IHC (6)
IHC-P (3)
WB (17)
ELISA (5)
IF (1)
IP (1)
Peptide-ELISA (1)
rabbit (22)
mouse (2)
Product Group
IHCPlus (1)
IgG (16)
IgG2a (2)
monoclonal mc (2)
polyclonal pc (22)
2A1 (2)
APC Conjugated (1)
Biotin Conjugated (3)
Carrier-free (1)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (1)
Unconjugated (13)
aa268-317 (4)
aa322-372 (1)
aa67-357 (1)
No (29)
Yes (1)
GST (1)
His (2)
Myc-DDK (Flag) (3)
Human (5)
293T Cells (1)
E. coli (2)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (2)
GMDS / GMD Antibody - Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
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GMDS / GMD Mouse anti-Human Monoclonal (2A1) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
GMDS / GMD Antibody - GMDS / GMD antibody Western Blot of Human heart.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GMDS / GMD Rabbit anti-Human Polyclonal (aa268-317) Antibody
Human
WB
Unconjugated
100 µl/$424
GMDS / GMD Antibody - GMDS / GMD antibody Western Blot of Human heart.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GMDS / GMD Rabbit anti-Human Polyclonal (aa268-317) (HRP) Antibody
Chicken, Bovine, Rabbit, Mouse, Dog, Rat, Hamster, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey
WB
HRP Conjugated
100 µl/$469
GMDS / GMD Antibody - GMDS / GMD antibody Western Blot of Human heart.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GMDS / GMD Rabbit anti-Human Polyclonal (aa268-317) (Biotin) Antibody
Chicken, Bovine, Rabbit, Mouse, Dog, Rat, Hamster, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
GMDS / GMD Antibody - GMDS / GMD antibody Western Blot of Human heart.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GMDS / GMD Rabbit anti-Human Polyclonal (aa268-317) (FITC) Antibody
Chicken, Bovine, Rabbit, Mouse, Dog, Rat, Hamster, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey
WB
FITC Conjugated
100 µl/$469
GMDS / GMD Antibody - IHC of paraffin-embedded DLD1 xenograft using GMDS antibody at 1:500 dilution.
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GMDS / GMD Rabbit anti-Human Polyclonal (aa67-357) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$450
GMDS / GMD Antibody - Immunohistochemistry image at a dilution of 1:400 and staining in paraffin-embedded human breast cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0) . Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4 °C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
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GMDS / GMD Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
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GMDS / GMD Rabbit anti-Human Polyclonal (HRP) Antibody
Human
HRP Conjugated
50 µg/$294; 100 µg/$360
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GMDS / GMD Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
Biotin Conjugated
50 µg/$294; 100 µg/$360
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GMDS / GMD Rabbit anti-Human Polyclonal (FITC) Antibody
Human
FITC Conjugated
50 µg/$294; 100 µg/$360
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GMDS / GMD Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$331
GMDS / GMD Antibody - Immunohistochemistry of paraffin-embedded Human tonsil tissue  using GMDS Polyclonal Antibody at dilution of 1:55(×200)
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GMDS / GMD Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
GMDS / GMD Antibody - Immunohistochemistry of paraffin-embedded Human tonsil tissue  using GMDS Polyclonal Antibody at dilution of 1:70(×200)
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GMDS / GMD Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
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GMDS / GMD Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µg/$357
GMDS / GMD Antibody - Western blot analysis GMDS using COLO205 whole cells lysates
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GMDS / GMD Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
GMDS / GMD Antibody - Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
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GMDS / GMD Mouse anti-Human Monoclonal (Carrier-free) (2A1) Antibody
Human
WB
Unconjugated, Carrier-free
100 µg/$511
Select
GMDS / GMD Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
100 µg/$749
Select
GMDS / GMD Rabbit anti-Human Polyclonal (HRP) Antibody
Mouse, Human
WB
HRP Conjugated
100 µl/$937
Select
GMDS / GMD Rabbit anti-Human Polyclonal (Biotin) Antibody
Mouse, Human
WB
Biotin Conjugated
100 µl/$937
Select
GMDS / GMD Rabbit anti-Human Polyclonal (FITC) Antibody
Mouse, Human
WB
FITC Conjugated
100 µl/$937
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GMDS / GMD Rabbit anti-Human Polyclonal (PE) Antibody
Mouse, Human
WB
PE Conjugated
100 µl/$937
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GMDS / GMD Rabbit anti-Human Polyclonal (APC) Antibody
Mouse, Human
WB
APC Conjugated
100 µl/$937
GMDS / GMD Antibody - Western blot analysis of extracts of HeLa cells, using GMDS antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 60s.
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GMDS / GMD Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
Select
GMDS / GMD Rabbit anti-Human Polyclonal (aa322-372) Antibody
Human
IP
Unconjugated
10 µg/$295; 100 µl/$514
GMDS / GMD Protein - Purified recombinant protein GMDS was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
41.8 kDa
20 µg/$1,107
Viewing 1-25 of 30 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).