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GM2A

GM2 ganglioside activator

The large binding pocket can accommodate several single chain phospholipids and fatty acids, GM2A also exhibits some calcium-independent phospholipase activity (By similarity). Binds gangliosides and stimulates ganglioside GM2 degradation. It stimulates only the breakdown of ganglioside GM2 and glycolipid GA2 by beta-hexosaminidase A. It extracts single GM2 molecules from membranes and presents them in soluble form to beta-hexosaminidase A for cleavage of N-acetyl-D-galactosamine and conversion to GM3.

Gene Name: GM2 ganglioside activator
Synonyms: GM2A, Ganglioside GM2 activator, GM2 ganglioside activator, GM2-AP, SAP-3
Target Sequences: NM_000405 NP_000396.2 P17900

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Antibodies (55)
Proteins (12)
ELISA Kits (3)
Development Kit (1)
Over-Expression Lysate (4)
Primary (55)
Recombinant (8)
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GM2A (70)
Human (57)
Mouse (15)
Rat (3)
Chimpanzee (3)
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IHC (9)
IHC-P (6)
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ELISA (27)
ICC (1)
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Peptide-ELISA (3)
rabbit (49)
mouse (4)
goat (2)
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monoclonal mc (3)
polyclonal pc (52)
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GM2A Antibody - Anti-GM2A antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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GM2A Rabbit anti-Human Polyclonal (Internal) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$440
GM2A Antibody - Anti-GM2A antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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GM2A Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$460
GM2A Antibody - Anti-GM2A antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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GM2A Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$460
GM2A Antibody - Anti-GM2A antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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GM2A Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$460
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GM2A Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA, WB
Unconjugated
100 µg/$414
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GM2A Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
GM2A Antibody - Detection limit for recombinant GST tagged GM2A is 0.3 ng/ml as a capture antibody.
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GM2A Mouse anti-Human Monoclonal (2C8) Antibody
Human
ELISA
Unconjugated
100 µg/$423
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GM2A Rabbit anti-Human Polyclonal (aa32-193) (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
GM2A Antibody - Immunofluorescence staining of GM2A in U251MG cells. Cells were fixed with 4% PFA, permeabilzed with 0.3% Triton X-100 in PBS, blocked with 10% serum, and incubated with rabbit anti-Human GM2A polyclonal antibody (dilution ratio 1:1000) at 4°C overnight. Then cells were stained with the Alexa Fluor 488-conjugated Goat Anti-rabbit IgG secondary antibody (green). Positive staining was localized to cytoplasm.
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GM2A Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Human
ELISA, ICC, IF, IHC-P
Unconjugated, Preservative Free
100 µl/$412
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GM2A Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IP, WB
Unconjugated
100 µg/$341
GM2A Antibody - GM2A was immunoprecipitated using: Lane A: 0.5 mg HeLa Whole Cell Lysate. 4 uL anti-GM2A rabbit polyclonal antibody and 60 ug of Immunomagnetic beads Protein A/G. Primary antibody: Anti-GM2A rabbit polyclonal antibody, at 1:100 dilution. Secondary antibody: Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size: 21 kDa. Observed band size: 21 kDa.
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GM2A Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Human
ELISA, IHC-P, IP, WB
Unconjugated, Preservative Free
100 µl/$412
GM2A Antibody - Immunohistochemistry of paraffin-embedded human kidney tissue using GM2A Antibody at dilution of 1:100
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GM2A Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$294; 100 µg/$360
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GM2A Mouse anti-Human Monoclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$361
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GM2A Rabbit anti-Human Polyclonal (aa25-54) Antibody
Mouse, Human
ELISA, WB
Unconjugated
200 µl/$734
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GM2A Rabbit anti-Human Polyclonal (aa25-54) (Biotin) Antibody
Mouse, Human
ELISA, WB
Biotin Conjugated
200 µl/$952
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GM2A Rabbit anti-Human Polyclonal (aa25-54) (APC) Antibody
Mouse, Human
ELISA, WB
APC Conjugated
200 µl/$952
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GM2A Rabbit anti-Human Polyclonal (aa25-54) (PE) Antibody
Mouse, Human
ELISA, WB
PE Conjugated
200 µl/$952
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GM2A Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$582
GM2A Antibody - Western blot All lanes: Ganglioside GM2 activator antibody at 2µg/ml + Rat kidney tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 21 kDa Observed band size: 21 kDa
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GM2A Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
50 µg/$294; 100 µg/$360
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GM2A Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
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GM2A Rabbit anti-Human Polyclonal (Biotin) Antibody
Mouse, Human
ELISA, IHC, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
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GM2A Rabbit anti-Human Polyclonal (FITC) Antibody
Mouse, Human
ELISA, IHC, WB
FITC Conjugated
50 µg/$294; 100 µg/$360
GM2A Antibody - Western blot analysis of extracts of HEK293 cells using GM2A antibody. The lane on the left was treated with blocking peptide.
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GM2A Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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GM2A Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, WB
HRP Conjugated
100 µg/$582
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GM2A Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
100 µg/$582
Viewing 1-25 of 70 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).