Rat GLRA1/GLRA2

Rabbit

Rat (tested or 100% immunogen sequence identity)

IgG Polyclonal

Unconjugated

Purified

Unmodified

Synthetic peptide corresponding to the N-Terminus of rat glycine receptor alpha 1 subunit.

N-Terminus

Recognizes an epitope within the N-terminal region (NT) of glycine receptor alpha 1 and alpha 2 subunits. Glycine receptors are members of the ligand-gated ion channel superfamily, which mediate fast inhibitory neurotransmission. The receptors are pentameric membrane proteins which form chloride channels. Binding of glycine to its receptor produces an increase in chloride conductance and membrane hyperpolarisation. Four genes encoding glycine receptor alpha subunits have been identified, together with a single beta polypeptide. Each subunit consists of a large extracellular N-terminal region, four transmembrane domains, and a large cytoplasmic domain.

• IHC - Frozen (1:1000)
• Western blot (1:1000)

Western Blot: LS-C43103 detects a band of approximately 48 kD in rat spinal cord lysates.

Ammonium Bicarbonate

Phosphate Buffered Saline (PBS)

Before reconstitution store at 4°C. After reconstitution store at -20°C. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.