GIT2

G protein-coupled receptor kinase interacting ArfGAP 2

GIT2 is a member of the GIT protein family, which interact with G protein-coupled receptor kinases and possess ADP-ribosylation factor (ARF) GTPase-activating protein (GAP) activity. GIT proteins traffic between cytoplasmic complexes, focal adhesions, and the cell periphery, and interact with Pak interacting exchange factor beta (PIX) to form large oligomeric complexes that transiently recruit other proteins. GIT proteins regulate cytoskeletal dynamics and participate in receptor internalization and membrane trafficking. This gene has been shown to repress lamellipodial extension and focal adhesion turnover, and is thought to regulate cell motility. This gene undergoes extensive alternative splicing to generate multiple isoforms, but the full-length nature of some of these variants has not been determined. The various isoforms have functional differences, with respect to ARF GAP activity and to G protein-coupled receptor kinase 2 binding.

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Products

Antibodies (32)

Proteins (9)

ELISA Kits (1)

Type

Cell-Based (1)

Over-Expression Lysate (6)

Primary (32)

Recombinant (3)

Target

GIT2 (42)

Reactivity

Human (33)

Mouse (7)

Rat (7)

Bovine (3)

Chicken (1)

Chimpanzee (3)

Dog (3)

Gibbon (3)

Horse (3)

Monkey (3)

Pig (3)

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Application

IHC (5)

IHC-P (5)

WB (25)

ELISA (8)

ICC (1)

IF (2)

IP (2)

Peptide-ELISA (2)

Host

rabbit (30)

mouse (2)

Product Group

IHCPlus (2)

Isotype

IgG (23)

IgG2a,k (1)

Clonality

monoclonal mc (1)

polyclonal pc (31)

Clone

3B5-B9 (1)

Format

96-Well Microplate (1)

APC Conjugated (1)

Biotin Conjugated (3)

FITC Conjugated (3)

HRP Conjugated (3)

PE Conjugated (1)

Unconjugated (21)

Epitope

aa486-535 (4)

aa500-550 (2)

330-410 aa, Internal (1)

Asp391 (1)

Internal (1)

Tyr592 (1)

aa361-410 (1)

aa600-650 (1)

aa714-749 (1)

Publications

No (42)

Sample Type

Adherent Cell Cultures (1)

Tag

GST (1)

GST, N-terminus (1)

Myc-DDK (Flag) (7)

Species

Human (6)

Source

293T Cells (3)

HEK 293 Cells (4)

Wheat Germ Extract (2)

Purification

Purified (1)

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IHC-plus™ GIT2 Antibody (clone 3B5-B9) LS-B7870

(4.0) Rating

Antibody:

GIT2 Mouse anti-Human Monoclonal (3B5-B9) Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

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IHC-plus™ GIT2 Antibody LS-B10868

(4.0) Rating

Antibody:

GIT2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ICC, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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GIT2 Antibody (aa361-410) LS-C119035

Antibody:

GIT2 Rabbit anti-Human Polyclonal (aa361-410) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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GIT2 Antibody LS-C395679

Antibody:

GIT2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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GIT2 Antibody (HRP) LS-C395669

Antibody:

GIT2 Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

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GIT2 Antibody (Biotin) LS-C395671

Antibody:

GIT2 Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

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GIT2 Antibody (FITC) LS-C395660

Antibody:

GIT2 Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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GIT2 Antibody LS-C809266

Antibody:

GIT2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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GIT2 Antibody (aa500-550) LS-C288859

Antibody:

GIT2 Rabbit anti-Human Polyclonal (aa500-550) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, IP

Format:

Unconjugated

Price:

10 µg/$295; 100 µl/$514

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GIT2 Antibody (aa500-550) LS-C286767

Antibody:

GIT2 Rabbit anti-Human Polyclonal (aa500-550) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

1 µg/$295; 100 µl/$532

Select

GIT2 Antibody LS-C822920

Antibody:

GIT2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

GIT2 Antibody (330-410 aa, Internal) LS-C383694

Antibody:

GIT2 Rabbit anti-Human Polyclonal (330-410 aa, Internal) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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GIT2 Antibody (aa600-650) LS-C288860

Antibody:

GIT2 Rabbit anti-Human Polyclonal (aa600-650) Antibody

Reactivity:

Human

Applications:

IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

Select

GIT2 Antibody LS-C752540

Antibody:

GIT2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated

Price:

100 µg/$341

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GIT2 Antibody LS-C310485

Antibody:

GIT2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$749

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GIT2 Antibody (Biotin) LS-C522200

Antibody:

GIT2 Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$937

• Unconjugated
• Biotin

• Unconjugated
• Biotin

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GIT2 Antibody LS-C658830

Antibody:

GIT2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$386

Select

GIT2 Antibody (Tyr592) LS-C778001

Antibody:

GIT2 Rabbit anti-Human Polyclonal (Tyr592) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$357

Select

GIT2 Antibody LS-C777922

Antibody:

GIT2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$357

Select

GIT2 Antibody (aa486-535) LS-C145412

Antibody:

GIT2 Rabbit anti-Human Polyclonal (aa486-535) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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GIT2 Antibody (aa714-749) LS-C344270

Antibody:

GIT2 Rabbit anti-Human Polyclonal (aa714-749) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

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GIT2 Antibody LS-C750335

Antibody:

GIT2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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GIT2 Antibody (Internal) LS-C356057

Antibody:

GIT2 Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Chicken, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$299

Select

GIT2 Antibody (Asp391) LS-C176810

Antibody:

GIT2 Rabbit anti-Human Polyclonal (Asp391) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

Select

GIT2 Antibody LS-C307702

Antibody:

GIT2 Mouse anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

50 µg/$705

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