GEMIN4

gem (nuclear organelle) associated protein 4

The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus.

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Products

Antibodies (26)

Proteins (3)

Type

Over-Expression Lysate (2)

Primary (26)

Recombinant (1)

Target

GEMIN4 (29)

Reactivity

Human (26)

Mouse (5)

Dog (3)

Gibbon (3)

Hamster (3)

Monkey (3)

Rabbit (3)

Application

IHC (4)

IHC-P (2)

WB (20)

ELISA (15)

IF (1)

IP (2)

Host

rabbit (20)

mouse (6)

Isotype

IgG (19)

IgG2b,k (6)

Clonality

monoclonal mc (6)

polyclonal pc (20)

Format

APC Conjugated (2)

Azide-free (1)

Biotin Conjugated (4)

FITC Conjugated (4)

HRP Conjugated (4)

PE Conjugated (2)

Unconjugated (10)

Epitope

aa273-301 (7)

aa287-336 (4)

aa1010-C-term (2)

aa959-1058 (1)

Publications

No (29)

Tag

GST, N-terminus (1)

Myc-DDK (Flag) (2)

Species

Human (2)

Source

293T Cells (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Select

GEMIN4 Antibody (aa287-336) LS-C107764

Antibody:

GEMIN4 Rabbit anti-Human Polyclonal (aa287-336) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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GEMIN4 Antibody (aa287-336, HRP) LS-C462375

Antibody:

GEMIN4 Rabbit anti-Human Polyclonal (aa287-336) (HRP) Antibody

Reactivity:

Rabbit, Mouse, Dog, Hamster, Gibbon, Human, Monkey

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

GEMIN4 Antibody (aa287-336, Biotin) LS-C462373

Antibody:

GEMIN4 Rabbit anti-Human Polyclonal (aa287-336) (Biotin) Antibody

Reactivity:

Rabbit, Mouse, Dog, Hamster, Gibbon, Human, Monkey

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

GEMIN4 Antibody (aa287-336, FITC) LS-C462374

Antibody:

GEMIN4 Rabbit anti-Human Polyclonal (aa287-336) (FITC) Antibody

Reactivity:

Rabbit, Mouse, Dog, Hamster, Gibbon, Human, Monkey

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

GEMIN4 Antibody LS-C672211

Antibody:

GEMIN4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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GEMIN4 Antibody (HRP) LS-C672214

Antibody:

GEMIN4 Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

Select

GEMIN4 Antibody (FITC) LS-C672212

Antibody:

GEMIN4 Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• FITC

• Unconjugated
• HRP
• FITC

Select

GEMIN4 Antibody (aa1010-C-term) LS-C287712

Antibody:

GEMIN4 Rabbit anti-Human Polyclonal (aa1010-C-term) Antibody

Reactivity:

Human

Applications:

IHC, IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

Select

GEMIN4 Antibody (aa1010-C-term) LS-C286699

Antibody:

GEMIN4 Rabbit anti-Human Polyclonal (aa1010-C-term) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

2.5 µg/$295; 100 µl/$532

Select

GEMIN4 Antibody LS-C665811

Antibody:

GEMIN4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IP, WB

Format:

Unconjugated

Price:

100 µg/$351

Select

GEMIN4 Antibody (aa959-1058) LS-C307670

Antibody:

GEMIN4 Mouse anti-Human Monoclonal (aa959-1058) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$705

Select

GEMIN4 Antibody (HRP) LS-C542315

Antibody:

GEMIN4 Mouse anti-Human Monoclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated

Price:

100 µl/$904

Select

GEMIN4 Antibody (Biotin) LS-C522183

Antibody:

GEMIN4 Mouse anti-Human Monoclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

100 µl/$904

Select

GEMIN4 Antibody (FITC) LS-C532227

Antibody:

GEMIN4 Mouse anti-Human Monoclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

100 µl/$904

Select

GEMIN4 Antibody (APC) LS-C513968

Antibody:

GEMIN4 Mouse anti-Human Monoclonal (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

100 µl/$904

Select

GEMIN4 Antibody (PE) LS-C650429

Antibody:

GEMIN4 Mouse anti-Human Monoclonal (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

100 µl/$904

• Unconjugated
• HRP
• Biotin
• FITC
• APC
• PE

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • APC
  • PE

Select

GEMIN4 Antibody LS-C830101

Antibody:

GEMIN4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

GEMIN4 Antibody (aa273-301) LS-C321609

Antibody:

GEMIN4 Rabbit anti-Human Polyclonal (aa273-301) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

GEMIN4 Antibody (aa273-301, Biotin) LS-C257667

Antibody:

GEMIN4 Rabbit anti-Human Polyclonal (aa273-301) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

GEMIN4 Antibody (aa273-301, FITC) LS-C257668

Antibody:

GEMIN4 Rabbit anti-Human Polyclonal (aa273-301) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

GEMIN4 Antibody (aa273-301, APC) LS-C257666

Antibody:

GEMIN4 Rabbit anti-Human Polyclonal (aa273-301) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

GEMIN4 Antibody (aa273-301, Azide-free, HRP) LS-C257669

Antibody:

GEMIN4 Rabbit anti-Human Polyclonal (aa273-301) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

Select

GEMIN4 Antibody (aa273-301, PE) LS-C257670

Antibody:

GEMIN4 Rabbit anti-Human Polyclonal (aa273-301) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• HRP, Azide-free
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • HRP, Azide-free
  • PE

Select

GEMIN4 Antibody (aa273-301) LS-C157771

Antibody:

GEMIN4 Rabbit anti-Human Polyclonal (aa273-301) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

Select

GEMIN4 Antibody LS-C497470

Antibody:

GEMIN4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

Viewing 1-25 of 29 product results

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