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Catalog Number Size Price
LS-C36583-500 500 µg $830 
Antibody

Monoclonal Rat anti‑Mouse GDF5 / GDF‑5 Antibody LS‑C36583

Monoclonal Rat anti‑Mouse GDF5 / GDF‑5 Antibody LS‑C36583

Antibody:
GDF5 / GDF-5 Rat anti-Mouse Monoclonal Antibody
Application:
ELISA, Func, Neut
Reactivity:
Mouse
Format:
Unconjugated, Unmodified
Price
Catalog Number
$830
LS-C36583-500
Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
GDF5 / GDF-5 Rat anti-Mouse Monoclonal Antibody
Application:
ELISA, Func, Neut
Reactivity:
Mouse
Format:
Unconjugated, Unmodified

Specifications

Description
GDF-5 antibody LS-C36583 is an unconjugated rat monoclonal antibody to mouse GDF-5 (GDF5). Validated for ELISA, Func and Neut.
Target
Mouse GDF5 / GDF-5
Synonyms
GDF5 | CDMP-1 | CDMP1 | GDF-5 | LAP4 | Radotermin | OS5 | BMP14 | SYNS2
Host
Rat
Reactivity
Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG2b Monoclonal
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified
Immunogen
E. coli-derived monomeric rmGDF-5.
Specificity
Recognizes mouse GDF-5 in direct ELISA. Does not cross-react with rmGDF-1, rmGDF-3, or rmGDF-8.
Applications
  • ELISA (0.5 - 1 µg/ml)
  • Functional Assay
  • Neutralization
Usage
Suitable for use in direct ELISA and Neutralization. Neutralization (ND50): ~2-10 ug/ml in the presence of 3 ug/ml of rmGDF-5, using the ATDC5 cell line. Note: The exact concentration of antibody required to neutralize rmGDF-5 activity is dependent on the cytokine concentration, cell type, growth conditions and the type of activity studied. The Neutralization Dose50 (ND50) for this antibody is defined as that concentration of antibody required to yield one-half maximal inhibition of the cytokine activity on a responsive cell line, when that cytokine is present at a concentration just high enough to elicit a maximum response. Direct ELISA: 0.5-1.0 ug/ml. The detection limit is ~10 ng/well.
Presentation
Lyophilized from PBS, 5% Trehalose
Reconstitution
Reconstitute in sterile PBS.
Storage
Store at -20°C lyophilized. Once reconstituted, aliquot and store at -20°C.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About GDF5 / GDF-5
P43026 NM_000557 NP_000548.2

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Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 9/19/2021