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| Catalog Number | Size | Price |
|---|---|---|
| LS-A4105-50 | 50 µg (1 mg/ml) | $460 |
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PathPlus™ Polyclonal Rabbit anti‑Human GALR1 / Galanin Receptor 1 Antibody (N‑Terminus, IHC) LS‑A4105
PathPlus™ Polyclonal Rabbit anti‑Human GALR1 / Galanin Receptor 1 Antibody (N‑Terminus, IHC) LS‑A4105
Antibody:
GALR1 / Galanin Receptor 1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Application:
IHC, IHC-P, ICC
Reactivity:
Human
Format:
Unconjugated, Unmodified
Overview
Antibody:
GALR1 / Galanin Receptor 1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Application:
IHC, IHC-P, ICC
Reactivity:
Human
Format:
Unconjugated, Unmodified
Specifications
Description
Galanin receptor 1 (GALR1) mediates the effects of the peptide galanin in a wide variety of tissues. Unlike GALR2, the primary signaling mechanism of GALR1 is by inhibiting adenylate cyclase through Gi. GALR1 regulates the GnRH neuroendocrine axis with its expression in POMC neurons. Pathogens like E. coli can cause diarrhea by increasing expression of Galanin Receptor 1 in the epithelial cells lining the colon, resulting in increased secretion of colonocyte chloride and fluid.
References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human GALR1 / Galanin Receptor 1
Synonyms
GALR1 | Galanin receptor type 1 | Galanin receptor 1 | Galanin receptor galr1 | Galanin-1 receptor | GALNR1 | Gal receptor 1 | Gal-r1 | Galn1r | Gal-1 receptor | GAL1-R | Galanin r1 receptor | GALNR | GALR-1 | Hugal 1-r
Host
Rabbit
Reactivity
Human
(tested or 100% immunogen sequence identity)
Predicted
Monkey (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 18 amino acid peptide from N-Terminus extracellular domain of human GALR1. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%); Marmoset (94%); Dog (89%); Panda, Horse (83%).
Epitope
N-Terminus
Specificity
Human GALR1. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except SSTR5 (50%).
Applications
- IHC
- IHC - Paraffin (19 µg/ml)
- ICC
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About GALR1 / Galanin Receptor 1
Validation
Lung, non small cell carcinoma
Lung, non small cell carcinoma
Brain, Parkinson's soft body
Brain, Parkinson's soft body
Anti-GALR1 / Galanin Receptor 1 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GALR1 / Galanin Receptor 1 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GALR1 / Galanin Receptor 1 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GALR1 / Galanin Receptor 1 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GALR1 antibody IHC of human brain, neurons. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GALR1 antibody IHC of human brain, neurons. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
See More About...
LSBio Ratings
PathPlus™ GALR1 / Galanin Receptor 1 Antibody (N-Terminus) for IHC, ICC LS-A4105 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human, Monkey
Applications:
IHC, IHC - Paraffin
Species:
Human
Applications:
IHC, IHC - Paraffin
Species:
Human
Applications:
Western blot, Flow Cytometry
Species:
Human, Monkey
Applications:
IHC, IHC - Paraffin
Species:
Human, Mouse
Applications:
Immunofluorescence, Peptide Enzyme-Linked Immunosorbent Assay
Species:
Human
Applications:
Western blot, Flow Cytometry, ELISA
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/19/2024
Date Requested: 4/19/2024
