GABRA5 antibody LS-C43097 is an unconjugated rabbit polyclonal antibody to GABRA5 from mouse and rat. Validated for WB.
(tested or 100% immunogen sequence identity)
GABRA5 antibody was raised against synthetic peptide corresponding to the C-Terminal region of the alpha 5 subunit of rat GABA A receptor ( C-TERMINAL ).
The alpha 5 subunit of gamma-aminobutyric acid A (GABAA ) receptor. GABAA receptors are GABA gated chloride channels, which are important mediators of neuronal inhibition in the mammalian central nervous system. Activation of the GABAA site results in increased intracellular chloride concentration and hyperpolarization of the cell. GABAA receptors are pentameric structures assembled from a family of distinct subunits. At least fourteen distinct subunits have been identified, which show distinct patterns of temporal and spatial expression. GABAA receptors may be modulated by several drug types including benzodiazepines and barbiturates, and by phosphorylation by protein kinase C (PKC) and protein kinase A (PKA).
Western Blot: LS-C43097 detects a band of approximately 55kD in rat brain membrane fractions.
10 mM HEPES, pH 7.5, 0.09% Sodium Azide, 50% Glycerol, 0.01% BSA
For research use only.