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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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GABRA5 Antibody (C‑Terminus) LS‑C43097
Note: This antibody replaces LS-C23746
GABRA5 antibody LS-C43097 is an unconjugated rabbit polyclonal antibody to GABRA5 from mouse and rat. Validated for WB.
Antibody
Catalog
Size
Price
LS-C43097-100
100 µl
$545

Popular GABRA5 Products

GABRA5 antibody Western blot of Mouse Liver lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Mouse, Human, Monkey, Rat, Bovine, Dog, Guinea pig, Horse, Pig, Rabbit, Chicken, Xenopus
Applications: Western blot
Immunohistochemistry of paraffin-embedded human glioma at dilution 1:100
Species: Human
Applications: IHC, IHC - Paraffin, ELISA
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY GABRA5 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-GABRA5.
Species: Human
Applications: Western blot
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY GABRA5 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-GABRA5.
Species: Human
Applications: Western blot
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY GABRA5 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-GABRA5.
Species: Human
Applications: Western blot

Product Description

GABRA5 antibody LS-C43097 is an unconjugated rabbit polyclonal antibody to GABRA5 from mouse and rat. Validated for WB.

Specifications

Target
Rat GABRA5
Synonyms
GABRA5, Alpha 5, GABA A receptor alpha 5
Host
Rabbit
Reactivity
Rat, Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Purified
Modifications
Unmodified
Applications
  • Western blot (1:1000)
Immunogen
GABRA5 antibody was raised against synthetic peptide corresponding to the C-Terminal region of the alpha 5 subunit of rat GABA A receptor ( C-TERMINAL ).
Epitope
C-Terminus
Specificity
The alpha 5 subunit of gamma-aminobutyric acid A (GABAA ) receptor. GABAA receptors are GABA gated chloride channels, which are important mediators of neuronal inhibition in the mammalian central nervous system. Activation of the GABAA site results in increased intracellular chloride concentration and hyperpolarization of the cell. GABAA receptors are pentameric structures assembled from a family of distinct subunits. At least fourteen distinct subunits have been identified, which show distinct patterns of temporal and spatial expression. GABAA receptors may be modulated by several drug types including benzodiazepines and barbiturates, and by phosphorylation by protein kinase C (PKC) and protein kinase A (PKA).
Usage
Western Blot: LS-C43097 detects a band of approximately 55kD in rat brain membrane fractions.
Presentation
10 mM HEPES, pH 7.5, 0.09% Sodium Azide, 50% Glycerol, 0.01% BSA
Restrictions
For research use only.
About GABRA5
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Transcript variants utilizing three different alternative non-coding first exons have been described. P31644 NM_000810 NP_000801.1


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Requested From: United States
Date Requested: 11/13/2018

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