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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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FZD6 / Frizzled 6 Antibody (N‑Terminus) IHC‑plus™ LS‑A4481
Frizzled 6 antibody LS-A4481 is an unconjugated rabbit polyclonal antibody to human Frizzled 6 (FZD6). Validated for IHC. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.
Catalog
Size
Price
LS-A4481-50
50 µg (1 mg/ml)
$425
In Stock for Immediate Shipment
Description
Frizzled 6 antibody LS-A4481 is an unconjugated rabbit polyclonal antibody to human Frizzled 6 (FZD6). Validated for IHC. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.
Target
Human FZD6 / Frizzled 6
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Predicted
Monkey, Bovine, Horse (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (14 µg/ml)
  • (applications tested for the base form of this product only)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Synthetic 17 amino acid peptide from N-terminal extracellular domain of human Frizzled-6. Percent identity with other species by BLAST analysis: Human (100%); Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Bovine, Horse (94%); Elephant, Pig, Opossum (88%); Panda, Bat, Rabbit (82%).
Blocking Peptide
LS-E28969 - Liquid - 50 µg - $145.00
Immunizing peptide used to generate LS-A4481. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
N-Terminus
Specificity
Human Frizzled-6. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except MTMR10 (47%).
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only.
About FZD6 / Frizzled 6
O60353 NM_003506 NP_003497.2

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Publications (1)

1
Common dysregulation of Wnt/Frizzled receptor elements in human hepatocellular carcinoma. Bengochea A, de Souza MM, Lefranois L, Le Roux E, Galy O, Chemin I, Kim M, Wands JR, Trepo C, Hainaut P, Scoazec JY, Vitvitski L, Merle P. British journal of cancer. 2008 99:143-50. (IHC-P; Human) [Full Text Article] [PubMed:18577996] [PMC:PMC2453022]

Customer Reviews (0)


Images

Immunohistochemistry

Anti-Frizzled 6 / FZD6 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 14 ug/ml.
Anti-Frizzled 6 / FZD6 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 14 ug/ml.

Immunohistochemistry

Anti-Frizzled 6 / FZD6 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 14 ug/ml.
Anti-Frizzled 6 / FZD6 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 14 ug/ml.

Immunohistochemistry

Anti-Frizzled 6 / FZD6 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 14 ug/ml.
Anti-Frizzled 6 / FZD6 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 14 ug/ml.

Immunohistochemistry

Anti-Frizzled 6 / FZD6 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 14 ug/ml.
Anti-Frizzled 6 / FZD6 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 14 ug/ml.

Immunohistochemistry

Anti-Frizzled 6 / FZD6 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 14 ug/ml.
Anti-Frizzled 6 / FZD6 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 14 ug/ml.

Immunohistochemistry

Anti-Frizzled 6 / FZD6 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 14 ug/ml.
Anti-Frizzled 6 / FZD6 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 14 ug/ml.

Immunohistochemistry

Anti-Frizzled 6 / FZD6 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 14 ug/ml.
Anti-Frizzled 6 / FZD6 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 14 ug/ml.

Immunohistochemistry

Anti-Frizzled 6 / FZD6 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 14 ug/ml.
Anti-Frizzled 6 / FZD6 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 14 ug/ml.

Requested From: United States
Date Requested: 12/10/2018
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