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Catalog Number Size Price
LS-C388075-100 100 µg $506 
FOS / c-FOS Antibody - Western blot testing of c-Fos antibody and Lane 1: HT1080; 2: COLO320 cell lysate

Polyclonal Rabbit anti‑Human FOS / c‑FOS Antibody (aa170‑187, WB) LS‑C388075

Polyclonal Rabbit anti‑Human FOS / c‑FOS Antibody (aa170‑187, WB) LS‑C388075

Antibody:
FOS / c-FOS Rabbit anti-Human Polyclonal (aa170-187) Antibody
Application:
WB
Reactivity:
Human, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Hamster, Horse, Pig, Rabbit, Sheep
Format:
Unconjugated, Unmodified
Price
Catalog Number
$506
LS-C388075-100
Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
FOS / c-FOS Rabbit anti-Human Polyclonal (aa170-187) Antibody
Application:
WB
Reactivity:
Human, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Hamster, Horse, Pig, Rabbit, Sheep
Format:
Unconjugated, Unmodified

Specifications

Description
C-FOS antibody LS-C388075 is an unconjugated rabbit polyclonal antibody to c-FOS (FOS) (aa170-187) from human. It is reactive with human, mouse, rat and other species. Validated for WB.
Target
Human FOS / c-FOS
Synonyms
FOS | Activator protein 1 | AP-1 | Cellular oncogene c-fos | Cellular oncogene fos | Proto-oncogene c-Fos | v-fos | C-FOS | G0s7 | p55
Host
Rabbit
Reactivity
Human, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Hamster, Horse, Pig, Rabbit, Sheep (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic peptide (DQLEDEKSALQTEIANLL, aa170-187 of UniProt P01100) was used as the immunogen for this c-Fos antibody (100% homologous in human, mouse and rat). Percent identity by BLAST analysis: Human, Mouse, Rat, Ferret, Sheep, Cat, Bovine, Bat, Hamster, Rabbit, Horse, Pig, Opossum, Guinea pig, Platypus, Dog (100%); Elephant (94%); Zebra finch, Chicken, Zebrafish (89%); Trout, Medaka, Pufferfish (83%).
Epitope
aa170-187
Specificity
Human FOS / c-FOS
Applications
  • Western blot (0.5 - 1 µg/ml)
Usage
The human oncogene c-Fos is the cellular homolog of the transforming gene of Finkel-Biskis-Jinkins (FBJ) murine osteosarcoma virus which was mapped to a single human chromosome. The protein is encoded by the FOS gene. It was the first transcription factor identified that has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is also a major component of the activator protein-1 (AP-1) transcription factor complex, which includes members of the JUN family. c-Fos is a major nuclear target for signal transduction pathways involved in the regulation of cell growth, differentiation, and transformation. Using transgenic and knockout mice, Grigoriadis et al. (1995) established a unique role for the proto-oncogene and nuclear transcription factor in regulating the differentiation and activity of specific bone cell populations, both during normal development and in bone disease.
Presentation
Lyophilized from PBS, 2.5% BSA, 0.025% sodium azide/thimerosal.
Reconstitution
Reconstitute in sterile distilled water.
Storage
Prior to reconstitution, 4°C. Following reconstitution store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About FOS / c-FOS
P01100 NM_005252 NP_005243.1

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Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 12/9/2021