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FLVCR / FLVCR1

feline leukemia virus subgroup C cellular receptor 1

Isoform 1: Heme transporter that exports cytoplasmic heme. It can also export coproporphyrin and protoporphyrin IX, which are both intermediate products in the heme biosynthetic pathway. Does not export bilirubin. Heme export depends on the presence of HPX and may be required to protect developing erythroid cells from heme toxicity. Heme export also provides protection from heme or ferrous iron toxicities in liver and brain. Causes susceptibility to FeLV-C in vitro. Required during erythtopoiesis to maintain intracellular free heme balance since in proerythroblasts, heme synthesis intensifies and it's accumulation is toxic for cells.Isoform 2: Heme transporter that promotes heme efflux from the mitochondrion to the cytoplasm. Essential for erythroid differentiation.

Gene Name: feline leukemia virus subgroup C cellular receptor 1
Synonyms: FLVCR1, PCA, PCARP, AXPC1, FLVCR, HFLVCR, MFSD7B
Target Sequences: NM_014053 NP_054772.1 Q9Y5Y0

Publications (1)

1
New Insights into the Pivotal Role of Iron/Heme Metabolism in TLR4/NF-?B Signaling-Mediated Inflammatory Responses in Human Monocytes. Dong Young Kang, Nipin Sp, Eun Seong Jo, Jin-Moo Lee, Kyoung-Jin Jang. Cells. 2021 September;10:2549. [Full Text Article] [PubMed:34685529] [PMC:PMC8534183] Related Antibodies: LS-C750126.

☰ Filters
Antibodies (21)
Proteins (4)
Over-Expression Lysate (2)
Primary (21)
Recombinant (2)
FLVCR / FLVCR1 (25)
Human (20)
Mouse (4)
Bat (3)
Bovine (3)
Dog (3)
Gibbon (3)
Guinea pig (3)
Horse (3)
Monkey (3)
Pig (3)
Rabbit (3)
IHC-P (1)
WB (19)
ELISA (7)
Peptide-ELISA (1)
rabbit (14)
mouse (6)
goat (1)
IgG (9)
IgG2b,k (6)
monoclonal mc (6)
polyclonal pc (15)
APC Conjugated (2)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (2)
Unconjugated (8)
aa223-272 (4)
aa1-84 (1)
aa543-555 (1)
No (24)
Yes (1)
GST (1)
GST, N-terminus (1)
Myc-DDK (Flag) (2)
Human (3)
293T Cells (1)
HEK 293 Cells (1)
Wheat Germ Extract (2)
Purified (1)
FLVCR / FLVCR1 Antibody - FLVCR1 / FLVCR antibody Western blot of Mouse Brain lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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FLVCR / FLVCR1 Rabbit anti-Mouse Polyclonal (aa223-272) Antibody
Mouse
WB
Unconjugated
100 µl/$424
FLVCR / FLVCR1 Antibody - FLVCR1 / FLVCR antibody Western blot of Mouse Brain lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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FLVCR / FLVCR1 Rabbit anti-Mouse Polyclonal (aa223-272) (HRP) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Gibbon, Human, Monkey
WB
HRP Conjugated
100 µl/$469
FLVCR / FLVCR1 Antibody - FLVCR1 / FLVCR antibody Western blot of Mouse Brain lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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FLVCR / FLVCR1 Rabbit anti-Mouse Polyclonal (aa223-272) (Biotin) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Gibbon, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
FLVCR / FLVCR1 Antibody - FLVCR1 / FLVCR antibody Western blot of Mouse Brain lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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FLVCR / FLVCR1 Rabbit anti-Mouse Polyclonal (aa223-272) (FITC) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Gibbon, Human, Monkey
WB
FITC Conjugated
100 µl/$469
FLVCR / FLVCR1 Antibody - Western blot analysis of extracts of Raji cells, using FLVCR1 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 60s.
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FLVCR / FLVCR1 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
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FLVCR / FLVCR1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$357
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FLVCR / FLVCR1 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µg/$749
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FLVCR / FLVCR1 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$937
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FLVCR / FLVCR1 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$937
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FLVCR / FLVCR1 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$937
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FLVCR / FLVCR1 Rabbit anti-Human Polyclonal (PE) Antibody
Human
WB
PE Conjugated
100 µl/$937
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FLVCR / FLVCR1 Rabbit anti-Human Polyclonal (APC) Antibody
Human
WB
APC Conjugated
100 µl/$937
FLVCR / FLVCR1 Antibody - Western blot analysis of extracts of Raji cells using FLVCR1 Polyclonal Antibody at dilution of 1:1000.
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FLVCR / FLVCR1 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
FLVCR / FLVCR1 Antibody - Immunochemical staining of human FLVCR1 in human kidney with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.
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FLVCR / FLVCR1 Rabbit anti-Human Polyclonal Antibody
Human
IHC-P
Unconjugated
100 µl/$412
FLVCR / FLVCR1 Protein - 12.5% SDS-PAGE of human FLVCR stained with Coomassie Blue
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Wheat Germ Extract
GST
86.3 kDa
10 µg/$479; 25 µg/$670
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FLVCR / FLVCR1 Mouse anti-Human Monoclonal (aa1-84) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$705
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FLVCR / FLVCR1 Mouse anti-Human Monoclonal (HRP) Antibody
Human
ELISA, WB
HRP Conjugated
100 µl/$904
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FLVCR / FLVCR1 Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
100 µl/$904
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FLVCR / FLVCR1 Mouse anti-Human Monoclonal (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
100 µl/$904
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FLVCR / FLVCR1 Mouse anti-Human Monoclonal (PE) Antibody
Human
ELISA, WB
PE Conjugated
100 µl/$904
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FLVCR / FLVCR1 Mouse anti-Human Monoclonal (APC) Antibody
Human
ELISA, WB
APC Conjugated
100 µl/$904
FLVCR / FLVCR1 Antibody - Antibody (0.1 ug/ml) staining of Human Bone Marrow lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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FLVCR / FLVCR1 Goat anti-Human Polyclonal (aa543-555) Antibody
Human
Peptide-ELISA
Unconjugated
100 µg/$503
FLVCR / FLVCR1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
FLVCR / FLVCR1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
59.7 kDa
20 µg/$150
FLVCR / FLVCR1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
59.7 kDa
100 µg/$494
Viewing 1-25 of 25 product results



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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).