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May play a critical role in death receptor-induced apoptosis and may target CASP8 and CASP10 to the nucleus. May regulate degradation of intermediate filaments during apoptosis. May play a role in the general transcription machinery in the nucleus and might be an important regulator of the activity of GTF3C3.
Gene Name: | death effector domain containing 2 |
Synonyms: | DEDD2, DED-containing protein FLAME-3, FLAME-3, FLAME3 |
Target Sequences: | NM_133328 NP_579874.1 Q8WXF8 |
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